• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

由高黏液性肺炎克雷伯菌引起的髂腰肌脓肿、椎体椎间盘炎、脓毒性肺栓塞和对称性外周坏疽

Iliopsoas Abscess, Spondylodiscitis, Septic Pulmonary Embolism, and Symmetrical Peripheral Gangrene by Hypermucoviscous Klebsiella pneumoniae.

作者信息

Hamada Hina, Hayashi Koji, Morikawa Yukie, Hayashi Maho, Shirasaki Akihisa, Yamamoto Chie

机构信息

Department of Internal Medicine, Fukui General Hospital, Fukui, JPN.

Department of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.

出版信息

Cureus. 2024 Aug 28;16(8):e67985. doi: 10.7759/cureus.67985. eCollection 2024 Aug.

DOI:10.7759/cureus.67985
PMID:39347316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11427936/
Abstract

Hypermucoviscous (hmKP) is a bacterium known to cause lesions, including abscesses, in various organs. Unlike typical , hmKP can yield a positive string test in culture specimens. Infections caused by hmKP often become severe and are associated with a poor prognosis. In this report, we describe a case of iliopsoas abscess, spondylodiscitis, septic pulmonary embolism, and symmetrical peripheral gangrene (SPG) caused by hmKP. The patient received non-invasive positive-pressure ventilation, hemodialysis, platelet transfusions, fresh frozen plasma, thrombomodulin, and intensive antibiotic therapy including rifampicin. The patient underwent 148 days of antibiotic therapy and achieved a good outcome.

摘要

高黏液性肺炎克雷伯菌（hmKP）是一种已知可在各个器官引起病变（包括脓肿）的细菌。与典型的肺炎克雷伯菌不同，hmKP在培养标本中可产生阳性拉丝试验结果。由hmKP引起的感染往往会变得严重且预后不良。在本报告中，我们描述了一例由hmKP引起的髂腰肌脓肿、脊椎椎间盘炎、感染性肺栓塞和对称性外周坏疽（SPG）病例。患者接受了无创正压通气、血液透析、血小板输注、新鲜冰冻血浆、血栓调节蛋白以及包括利福平在内的强化抗生素治疗。患者接受了148天的抗生素治疗并取得了良好的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/9c99f9adf1bf/cureus-0016-00000067985-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/19c7bba02b73/cureus-0016-00000067985-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/7d112abff6b3/cureus-0016-00000067985-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/0e6b951c4fc4/cureus-0016-00000067985-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/9c99f9adf1bf/cureus-0016-00000067985-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/19c7bba02b73/cureus-0016-00000067985-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/7d112abff6b3/cureus-0016-00000067985-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/0e6b951c4fc4/cureus-0016-00000067985-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/11427936/9c99f9adf1bf/cureus-0016-00000067985-i04.jpg

相似文献

1
Iliopsoas Abscess, Spondylodiscitis, Septic Pulmonary Embolism, and Symmetrical Peripheral Gangrene by Hypermucoviscous Klebsiella pneumoniae.由高黏液性肺炎克雷伯菌引起的髂腰肌脓肿、椎体椎间盘炎、脓毒性肺栓塞和对称性外周坏疽
Cureus. 2024 Aug 28;16(8):e67985. doi: 10.7759/cureus.67985. eCollection 2024 Aug.
2
Differences in severity of bacteraemia caused by hypermucoviscous and non-hypermucoviscous Klebsiella pneumoniae.产超黏液与非产超黏液肺炎克雷伯菌引起菌血症严重程度的差异。
Int J Antimicrob Agents. 2023 May;61(5):106767. doi: 10.1016/j.ijantimicag.2023.106767. Epub 2023 Feb 28.
3
Bloodstream infections caused by Klebsiella pneumoniae: prevalence of bla, virulence factors and their impacts on clinical outcome.肺炎克雷伯菌血流感染：bla 的流行情况、毒力因子及其对临床结局的影响。
BMC Infect Dis. 2018 Jul 31;18(1):358. doi: 10.1186/s12879-018-3263-x.
4
Identification and Characterization of NDM-1-producing Hypervirulent (Hypermucoviscous) in China.中国产 NDM-1 超级毒力（超粘液性）的鉴定和特征。
Ann Lab Med. 2019 Mar;39(2):167-175. doi: 10.3343/alm.2019.39.2.167.
5
Clinical and genomic analysis of hypermucoviscous isolates: Identification of new hypermucoviscosity associated genes.临床和基因组分析高黏液性分离株：鉴定新的高黏液性相关基因。
Front Cell Infect Microbiol. 2023 Jan 4;12:1063406. doi: 10.3389/fcimb.2022.1063406. eCollection 2022.
6
Microbiological and Clinical Characteristics of Hypermucoviscous Isolates Associated with Invasive Infections in China.中国侵袭性感染相关高黏液性分离株的微生物学及临床特征
Front Cell Infect Microbiol. 2017 Feb 1;7:24. doi: 10.3389/fcimb.2017.00024. eCollection 2017.
7
[A case of liver abscess caused by hypermucoviscous Klebsiella pneumoniae with septic pulmonary embolism].[1例由高黏液性肺炎克雷伯菌引起的肝脓肿合并脓毒性肺栓塞]
Nihon Shokakibyo Gakkai Zasshi. 2020;117(5):437-445. doi: 10.11405/nisshoshi.117.437.
8
Antimicrobial susceptibility and microbiological and epidemiological characteristics of hypermucoviscous Klebsiella pneumoniae strains in a tertiary hospital in Hangzhou, China.中国杭州一家三级医院产超广谱β-内酰胺酶肺炎克雷伯菌的药敏性及微生物学和流行病学特征。
J Glob Antimicrob Resist. 2018 Dec;15:61-64. doi: 10.1016/j.jgar.2018.05.025. Epub 2018 Jun 6.
9
Two unusual cases of successful treatment of hypermucoviscous Klebsiella pneumoniae invasive syndrome.两例成功治疗高黏液性肺炎克雷伯菌侵袭综合征的罕见病例。
BMC Infect Dis. 2016 Nov 16;16(1):680. doi: 10.1186/s12879-016-2011-3.
10
Septic Meningitis and Liver Abscess due to Hypermucoviscous Klebsiella pneumoniae Complicated with Chronic Strongyloidiasis in a Human T-lymphotropic Virus 1 Carrier.人类嗜T淋巴细胞病毒1型携带者中，高黏液性肺炎克雷伯菌引起的脓毒性脑膜炎和肝脓肿并发慢性类圆线虫病
Intern Med. 2020 Jan 1;59(1):129-133. doi: 10.2169/internalmedicine.3403-19. Epub 2019 Aug 21.

本文引用的文献

1
Rifampicin exerts anti-mucoviscous activity against hypervirulent Klebsiella pneumoniae via binding to the RNA polymerase β subunit.利福平通过与RNA聚合酶β亚基结合，对高毒力肺炎克雷伯菌发挥抗黏液活性。
J Glob Antimicrob Resist. 2023 Mar;32:21-28. doi: 10.1016/j.jgar.2022.11.018. Epub 2022 Dec 23.
2
Successful treatment of hypervirulent bacteremia with combination carbapenem and rifampicin.联合使用碳青霉烯类药物和利福平成功治疗高毒力菌血症。
IDCases. 2021 Sep 2;26:e01276. doi: 10.1016/j.idcr.2021.e01276. eCollection 2021.
3
Hypervirulent Klebsiella pneumoniae - clinical and molecular perspectives.
高毒力肺炎克雷伯菌：临床与分子视角
J Intern Med. 2020 Mar;287(3):283-300. doi: 10.1111/joim.13007. Epub 2019 Nov 21.
4
Invasive Klebsiella pneumoniae infections, California, USA.美国加利福尼亚州侵袭性肺炎克雷伯菌感染
Emerg Infect Dis. 2010 Sep;16(9):1490-1. doi: 10.3201/eid1609.100386.
5
K2 serotype Klebsiella pneumoniae causing a liver abscess associated with infective endocarditis.K2 血清型肺炎克雷伯菌引起肝脓肿合并感染性心内膜炎。
J Clin Microbiol. 2010 Feb;48(2):639-41. doi: 10.1128/JCM.01779-09. Epub 2009 Dec 9.
6
Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates: association with invasive syndrome in patients with community-acquired bacteraemia.肺炎克雷伯菌分离株高黏液性表型的临床意义：与社区获得性菌血症患者侵袭性综合征的关联
J Intern Med. 2006 Jun;259(6):606-14. doi: 10.1111/j.1365-2796.2006.01641.x.
7
Symmetrical peripheral gangrene complicating Klebsiella pneumoniae sepsis associated with antiphospholipid antibodies.与抗磷脂抗体相关的肺炎克雷伯菌败血症并发对称性外周坏疽。
Ann Rheum Dis. 2004 Apr;63(4):459-60. doi: 10.1136/ard.2003.012542.
8
Symmetrical peripheral gangrene.对称性外周坏疽
Trop Doct. 2004 Jan;34(1):2-4. doi: 10.1177/004947550403400102.
9
Klebsiella pneumoniae liver abscess associated with septic endophthalmitis.肺炎克雷伯菌肝脓肿合并感染性眼内炎。
Arch Intern Med. 1986 Oct;146(10):1913-6.