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类风湿关节炎常用基础药物的比较疗效(长期随机研究)

[Comparative effectiveness of the basic drugs used in rheumatoid arthritis (long-term randomized study)].

作者信息

Tsvetkova E S

出版信息

Ter Arkh. 1985;57(8):40-3.

PMID:3934779
Abstract

Study of the comparative efficacy of the basic slow-acting drugs for the treatment of rheumatoid arthritis permits considering randomization as necessary for obtaining objective data. It has been established that gold salts (chrisanol and myochrysin) are the most efficacious drugs for the treatment of RA. D-Penicillamine and delagil, in particular, are less efficacious. Administration of levamisole is rather dangerous because of the frequency and intensity of side effects.

摘要

对治疗类风湿性关节炎的基本慢效药物的比较疗效研究允许视获取客观数据的必要性进行随机分组。已证实金盐(克立沙醇和硫代葡萄糖金)是治疗类风湿性关节炎最有效的药物。尤其是D-青霉胺和地来洛尔疗效较差。由于副作用出现的频率和强度,左旋咪唑的使用相当危险。

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