Division of Urology, Connecticut Children's, Hartford, CT, USA.
Curr Urol Rep. 2024 Sep 30;26(1):5. doi: 10.1007/s11934-024-01230-8.
This review aims to highlight background of contributing factors for suboptimal nutrition in individuals with spina bifida and introduce strategies for amelioration.
Recent studies demonstrate increased risk of metabolic syndrome by neurosegmental level, which is associated with truncal obesity and reduced mobility. From the neonatal intensive care stay, which may disrupt breast feeding and the developing microbiome of the gastrointestinal tract, to early childhood various insults may lead to suboptimal feeding practices, preferences and dietary intake. Family coping skills, financial stressors may lead to food insecurity and/or residence in an area with limited availability of fresh food. As children grow, weakness and challenging transfers may lead to more sedentary lifestyle and weight gain despite limited linear growth. Body habitus changes including atrophy of the lower extremities may lead to decreased muscle mass and reduced energy expenditure, with predisposition to truncal obesity and metabolic syndrome.
本文旨在强调导致脊柱裂患者营养状况不佳的相关因素,并介绍改善这一状况的策略。
最近的研究表明,神经节段水平与躯干肥胖和活动能力降低有关,增加了代谢综合征的风险。从新生儿重症监护病房开始,这可能会干扰母乳喂养和胃肠道的微生物群发育,到幼儿期的各种伤害都可能导致喂养习惯、偏好和饮食摄入不佳。家庭应对技能、经济压力可能导致粮食不安全和/或居住在新鲜食品供应有限的地区。随着孩子的成长,虚弱和转移困难可能导致更多的久坐生活方式和体重增加,尽管线性生长有限。身体形态的变化,包括下肢萎缩,可能导致肌肉量减少和能量消耗减少,从而易患躯干肥胖和代谢综合征。