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肠道准备和开放及腹腔镜泌尿外科手术中抗菌预防的进展。

Advances in Bowel Preparation and Antimicrobial Prophylaxis for Open and Laparoscopic Urologic Surgery.

机构信息

Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287-2101, USA.

Department of Urology, George Washington University Hospital, Washington, DC 20037, USA.

出版信息

Urol Clin North Am. 2024 Nov;51(4):445-465. doi: 10.1016/j.ucl.2024.06.005. Epub 2024 Aug 17.

Abstract

Surgical site infections (SSIs) represent a major source of postoperative complications adversely impacting morbidity and mortality indices in surgical care. The discovery of antibiotics in the mid-20th century, and their ensuing use for preoperative antimicrobial bowel preparation and prophylaxis, drastically reduced the occurrence of SSIs providing a major tool to surgeons of various specialties, including urology. Because, the appropriate use of these antimicrobials is critical for their continued safety and efficacy, an understanding of the recommendations guiding their application is essential for all surgeons. Here, we comprehensively review these recommendations with a focus on open and laparoscopic urologic surgeries.

摘要

手术部位感染(SSI)是术后并发症的主要来源,对手术治疗的发病率和死亡率指标有不利影响。抗生素在 20 世纪中叶被发现,随后用于术前抗菌肠道准备和预防,极大地降低了 SSI 的发生,为包括泌尿科在内的各种专业的外科医生提供了主要工具。因为,这些抗生素的正确使用对其持续的安全性和有效性至关重要,所以所有外科医生都必须了解指导其应用的建议。在这里,我们全面审查了这些建议,重点是开放和腹腔镜泌尿外科手术。

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