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碘海醇与甲泛葡胺用于颈椎脊髓造影:双盲试验

Iohexol versus metrizamide for cervical myelography: double-blind trial.

作者信息

Gebarski S S, Gabrielsen T O, Knake J E, Latack J T, Yang P J, Hoff J T

出版信息

AJNR Am J Neuroradiol. 1985 Nov-Dec;6(6):923-6.

Abstract

Cervical myelography was performed by lateral C1-C2 puncture in 60 patients. Thirty patients received iohexol (an investigational aqueous contrast agent) and 30 received metrizamide in order to provide a prospective, randomized, double-blind trial comparing these contrast media. The two media produced radiographs of equal quality. Contrast-related morbidity was suffered by four patients (13%) in the iohexol group and by 11 patients (37%) in the metrizamide group. These features indicate that iohexol is superior to metrizamide as a contrast agent for cervical myelography.

摘要

对60例患者采用C1 - C2外侧穿刺进行颈椎脊髓造影。30例患者接受碘海醇(一种研究用的水性造影剂),30例患者接受甲泛葡胺,以进行一项比较这两种造影剂的前瞻性、随机、双盲试验。两种造影剂产生的X线片质量相同。碘海醇组有4例患者(13%)出现与造影剂相关的并发症,甲泛葡胺组有11例患者(37%)出现。这些特征表明,作为颈椎脊髓造影的造影剂,碘海醇优于甲泛葡胺。

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