C1-C2 myelography with iohexol and metrizamide: comparative study.

Comparison of metrizamide and iohexol contrast media for myelography performed via lateral C1-C2 puncture in a total of 64 patients demonstrated superiority of iohexol with respect to the incidence of postprocedure adverse reactions. There was no significant difference between the two media in quality of radiographic demonstration in the cervical region. Patients in whom posterior fossa positive-contrast radiographic examinations were performed at the same time as myelography, using either water-soluble agent, did not demonstrate any increased incidence of side effects over those having myelography alone.