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泰国儿童住院溺水的流行病学和结局:2015-2019 年全国数据分析。

The epidemiology and outcomes of hospitalized drowning in Thai children: a national data analysis 2015-2019.

机构信息

Department of Pediatrics, Faculty of Medicine, Khon Kaen University, 123/2000 Mitraparp Rd, Muang, Khon Kaen, 40002, Thailand.

Clinical Epidemiology unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

Scand J Trauma Resusc Emerg Med. 2024 Sep 30;32(1):98. doi: 10.1186/s13049-024-01270-6.

Abstract

BACKGROUND

Drowning remains a common cause of death among children. However, the epidemiology and impact of drowning in Thailand was underexplored. This study aimed to analyze the epidemiology and clinical outcomes of pediatric drowning in Thailand and to determine the factors associated with the need for intubation and mortality.

METHODS

Data derived from the Thai healthcare delivery system for the period between 2015 and 2019 were used to examine the monthly admissions, mortality rates, length of hospital stay, and the number of patients who received endotracheal intubation. Multivariate logistic regression analysis was employed to identify the risk factors associated with the need for intubation and mortality.

RESULTS

Of the 4,911, 58.8% were under six years old, 63.5% were male, and 31.2% were from the Northeastern region. The majority drowned during April, which is the summer season in Thailand. Among these patients, 28.8% required intubation, with the highest proportion found in the 6-<12 years age group (35.9%). The independent risk factors for intubation were metabolic acidosis (adjusted odd ratio [aOR] 9.74; 95% confidence interval [CI] 7.14-13.29; p < 0.001) and pulmonary edema (aOR 5.82; 95%CI 3.92-8.65; p < 0.001). The overall mortality rate due to drowning was 12.6%. Factors significantly associated with mortality included in-hospital cardiac arrest (aOR 4.43; 95%CI 2.78-7.06; p < 0.001), and the presence of drowning-related complications, particularly renal failure (aOR 7.13; 95%CI 3.93-12.94; p < 0.001).

CONCLUSION

Drowning admissions and mortality were highest among male children under six years old, occurring mainly during the summer season. Significant factors associated with intubation requirement included metabolic acidosis and pulmonary edema. The mortality was significantly associated with in-hospital cardiac arrest and drowning-related complications, particularly renal failure.

TRIAL REGISTRATION

This is an observational study, does not include any intervention, and has therefore not been registered.

摘要

背景

溺水仍然是儿童死亡的常见原因。然而,泰国溺水的流行病学和影响仍未得到充分探索。本研究旨在分析泰国儿科溺水的流行病学和临床结果,并确定与插管和死亡率相关的因素。

方法

本研究使用 2015 年至 2019 年泰国医疗保健系统的数据,检查每月入院人数、死亡率、住院时间以及接受气管插管的患者人数。采用多变量逻辑回归分析确定与插管和死亡率相关的危险因素。

结果

在 4911 名患者中,58.8%的患者年龄在 6 岁以下,63.5%为男性,31.2%来自东北地区。大多数患者溺水发生在 4 月,这是泰国的夏季。这些患者中有 28.8%需要插管,6-<12 岁年龄组的比例最高(35.9%)。插管的独立危险因素是代谢性酸中毒(调整后的优势比[aOR]9.74;95%置信区间[CI]7.14-13.29;p<0.001)和肺水肿(aOR 5.82;95%CI 3.92-8.65;p<0.001)。溺水总死亡率为 12.6%。与死亡率显著相关的因素包括院内心搏骤停(aOR 4.43;95%CI 2.78-7.06;p<0.001),以及溺水相关并发症的存在,特别是肾衰竭(aOR 7.13;95%CI 3.93-12.94;p<0.001)。

结论

溺水入院和死亡率在 6 岁以下男性儿童中最高,主要发生在夏季。与插管需求相关的显著因素包括代谢性酸中毒和肺水肿。死亡率与院内心搏骤停和溺水相关并发症,特别是肾衰竭显著相关。

试验注册

这是一项观察性研究,不包括任何干预措施,因此尚未注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f16f/11441098/1c27938f8b76/13049_2024_1270_Fig1_HTML.jpg

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