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改善或恶化的全球变化率-髌股疼痛患者在评价治疗效果时意味着什么?

Global Rating of Change for Better or Worse-What Does It Mean When Patients Who Are Treated for Patellofemoral Pain Rate Their Change?

出版信息

J Orthop Sports Phys Ther. 2024 Oct;54(10):657-671. doi: 10.2519/jospt.2024.12120.

DOI:10.2519/jospt.2024.12120
PMID:39350592
Abstract

To investigate how a global rating of change (GROC) score corresponds to change in Knee injury and Osteoarthritis Outcome Score (KOOS) subscales in people with patellofemoral pain (PFP). Secondary analysis of data from 3 clinical trials. Four hundred ninety adolescents (10-18 years old) and adults (19-40 years old) with PFP completed KOOS (5 subscales, 0-100) at baseline and 3-month follow-up as well as GROC at 3-month follow-up. GROC category descriptors were mapped to 5 categories: worse, no change, a bit better, better, and much better. Gaussian approximation was then used to calculate the change in KOOS scores for each GROC category. Due to overlap between KOOS scores in "no change" and "a bit better," all analyses were performed on 4 categories. For all KOOS subscales, patients who reported being "worse" had negative KOOS scale change scores (≤ -2); patients reporting "no change" had KOOS scale change scores that ranged from -5 to 14; and patients feeling "better" or "much better" had positive KOOS scale change scores that ranged from 4 to 26 and ≥16, respectively. When patients with PFP reported feeling "worse," "better," or "much better," there was a small-to-substantial change across the different KOOS scales. This is in contrast to no difference between reporting "a bit better" or "no change" in KOOS. When patients say they feel a little better, clinicians should be less confident about whether change has truly occurred. .

摘要

为了探究整体变化评分(GROC)与髌股疼痛综合征(PFP)患者的膝关节损伤和骨关节炎结果评分(KOOS)亚量表变化之间的关系,对 3 项临床试验的数据进行了二次分析。490 名青少年(10-18 岁)和成年人(19-40 岁)在基线和 3 个月随访时完成了 KOOS(5 个亚量表,0-100),并在 3 个月随访时完成了 GROC。GROC 类别描述符被映射到 5 个类别:变差、无变化、略有改善、改善和显著改善。然后使用高斯逼近计算每个 GROC 类别中 KOOS 评分的变化。由于“无变化”和“略有改善”之间的 KOOS 评分重叠,因此所有分析均在 4 个类别上进行。对于所有 KOOS 亚量表,报告“变差”的患者具有负的 KOOS 量表变化评分(≤-2);报告“无变化”的患者 KOOS 量表变化评分在-5 到 14 之间;而报告“改善”或“显著改善”的患者的 KOOS 量表变化评分分别在 4 到 26 和≥16 之间。当 PFP 患者报告感觉“变差”、“改善”或“显著改善”时,不同 KOOS 量表之间存在较小到较大的变化。这与报告 KOOS 中“略有改善”或“无变化”之间没有差异形成对比。当患者说他们感觉好一点时,临床医生应该对是否真正发生了变化不太有信心。

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