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一种根据耐药性评估来杀死癌细胞的逻辑激活纳米开关。

A logic-activated nanoswitch for killing cancer cells according to assessment of drug-resistance.

作者信息

Zhang Lihua, Deng Xiangxi, Qing Zhihe, Lei Yanli, Feng Feng, Yang Ronghua, Zou Zhen

机构信息

College of Chemistry and Chemical Engineering, Shanxi Datong University Datong 037009 China

Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Biological Engineering, Changsha University of Science and Technology Changsha 410004 China.

出版信息

RSC Adv. 2024 Sep 30;14(42):31165-31169. doi: 10.1039/d4ra04651j. eCollection 2024 Sep 24.

DOI:10.1039/d4ra04651j
PMID:39351405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11440625/
Abstract

A logic-activated nanoswitch that could diagnose the differences between drug-resistant and non-drug-resistant cancer cells and control the release of drugs was developed for enhanced chemo-gene therapy using a standalone system. Compared to traditional treatments, the nanoswitch displayed improved anti-tumor efficiency .

摘要

一种逻辑激活的纳米开关被开发出来，它可以诊断耐药癌细胞和非耐药癌细胞之间的差异，并控制药物释放，以使用独立系统增强化学基因治疗。与传统治疗方法相比，该纳米开关显示出更高的抗肿瘤效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/136aadc5f43b/d4ra04651j-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/b8262ea290b7/d4ra04651j-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/51fa08f66403/d4ra04651j-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/6d7a7e25f146/d4ra04651j-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/810f5ec16b8d/d4ra04651j-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/136aadc5f43b/d4ra04651j-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/b8262ea290b7/d4ra04651j-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/51fa08f66403/d4ra04651j-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/6d7a7e25f146/d4ra04651j-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/810f5ec16b8d/d4ra04651j-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79db/11440625/136aadc5f43b/d4ra04651j-f5.jpg

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