Henan Joint International Research Laboratory of Green Construction of Functional Molecules and Their Bioanalytical Applications, College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, P. R. China.
Nanoscale Horiz. 2019 Mar 1;4(2):321-338. doi: 10.1039/c8nh00274f. Epub 2018 Nov 29.
As one kind of redox active layered transition-metal dioxide nanomaterials, single-layer manganese dioxide (MnO) nanosheets have gained significant research attention in the fields of biosensing and biomedicine because of their large surface area, intense and broad optical absorption, strong oxidation ability, catalytic activity, and robust mechanical properties. This review provides a brief overview of the recent advances in the development of MnO nanosheet-based biosensors, bioimaging as well as drug delivery for cancer therapy. The methodologies for the preparation of MnO nanosheets are summarized, followed by an introduction of the nanostructure and properties of MnO nanosheets. Special attention is paid to their applications in biosensing, bioimaging and cancer therapy. Future perspectives and the challenges of high-performance MnO nanosheets are also discussed.
作为一种氧化还原活性层状过渡金属二氧化物纳米材料，单层二氧化锰 (MnO) 纳米片因其具有大的表面积、强烈和广泛的光吸收、强氧化能力、催化活性和坚固的机械性能，在生物传感和生物医学领域引起了广泛关注。本综述简要概述了基于 MnO 纳米片的生物传感器、生物成像以及癌症治疗药物输送的最新进展。总结了制备 MnO 纳米片的方法，随后介绍了 MnO 纳米片的纳米结构和性质。特别关注它们在生物传感、生物成像和癌症治疗中的应用。还讨论了高性能 MnO 纳米片的未来展望和挑战。
