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保留瓣膜与跨环补片法修复法洛四联症术后的心电图变化:一项回顾性观察研究。

Electrocardiogram changes post surgical repair of tetralogy of Fallot with valve-sparing versus transannular patch: A retrospective observational study.

作者信息

Kindi Hamood Al, Battashi Sultan Al, Lawati Moosa Al, Abri Ismail Al, Maddali Madan Mohan

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Sultan Qaboos University Hospital, Oman.

Department of Child Health, The Royal Hospital, Muscat, Oman.

出版信息

Glob Cardiol Sci Pract. 2024 Aug 1;2024(4):e202428. doi: 10.21542/gcsp.2024.28.

Abstract

Long-term survival after tetralogy of Fallot (TOF) repair depends on several factors including the extent of chronic right ventricular adaptation to surgery. QRS duration (QRSd) is an important determinant of life-threatening arrhythmia post-TOF repair. This single-center retrospective study was designed to evaluate changes in QRSd post-TOF repair using either a pulmonary valve-sparing approach (VSA) or transannular patch (TAP). Data from patients who underwent TOF repair between January 2016 and December 2019 were analyzed to compare the changes in the QRSd following intracardiac repair after VSA (Group 1) or TAP (Group 2). Among the 105 patients who underwent TOF surgical repair, 60 were included in the study (Group 1:30 vs. Group 2:30). Electrocardiograms (ECGs) were recorded pre- and post-surgery. The primary outcome was to compare the change in QRSd (ΔQRSd) before and after surgery between the two groups. The mean length of postoperative follow-up was 35.9 months in group 1 and 34.47 months in group 2. The mean [SD] difference in QRSd values (QRSd2 - QRSd1) was shorter in Group 1 (45.67 [22.79] ms) than in Group 2 (49.63 [23.76] ms); however, these differences were not statistically significant ( = 0.428). The PR interval was similar between the two groups in both preoperative and postoperative ECG. At the short-term follow-up, both surgical approaches (VSA and TAP) resulted in similar QRSd post-TOF repair. Studies with longer follow-up periods are required to evaluate the association of the surgical approach with prolongation of QRSd and mortality.

摘要

法洛四联症(TOF)修复术后的长期生存取决于多种因素,包括慢性右心室对手术的适应程度。QRS波时限(QRSd)是TOF修复术后危及生命的心律失常的重要决定因素。本单中心回顾性研究旨在评估采用保留肺动脉瓣方法(VSA)或跨环补片(TAP)进行TOF修复术后QRSd的变化。分析了2016年1月至2019年12月期间接受TOF修复的患者的数据,以比较VSA(第1组)或TAP(第2组)心内修复术后QRSd的变化。在105例行TOF手术修复的患者中,60例纳入研究(第1组:30例 vs. 第2组:30例)。术前和术后均记录心电图(ECG)。主要结局是比较两组手术前后QRSd的变化(ΔQRSd)。第1组术后平均随访时间为35.9个月,第2组为34.47个月。第1组QRSd值的平均[标准差]差异(QRSd2 - QRSd1)(45.67 [22.79] ms)短于第2组(49.63 [23.76] ms);然而,这些差异无统计学意义(P = 0.428)。术前和术后ECG两组的PR间期相似。在短期随访中,两种手术方法(VSA和TAP)在TOF修复术后的QRSd相似。需要进行更长随访期的研究来评估手术方法与QRSd延长和死亡率之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f657/11439427/aa54b420a19b/gcsp-2024-4-e202428-g001.jpg

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