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保留瓣膜与跨环补片法修复法洛四联症术后的心电图变化:一项回顾性观察研究。

Electrocardiogram changes post surgical repair of tetralogy of Fallot with valve-sparing versus transannular patch: A retrospective observational study.

作者信息

Kindi Hamood Al, Battashi Sultan Al, Lawati Moosa Al, Abri Ismail Al, Maddali Madan Mohan

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Sultan Qaboos University Hospital, Oman.

Department of Child Health, The Royal Hospital, Muscat, Oman.

出版信息

Glob Cardiol Sci Pract. 2024 Aug 1;2024(4):e202428. doi: 10.21542/gcsp.2024.28.

DOI:10.21542/gcsp.2024.28
PMID:39351470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439427/
Abstract

Long-term survival after tetralogy of Fallot (TOF) repair depends on several factors including the extent of chronic right ventricular adaptation to surgery. QRS duration (QRSd) is an important determinant of life-threatening arrhythmia post-TOF repair. This single-center retrospective study was designed to evaluate changes in QRSd post-TOF repair using either a pulmonary valve-sparing approach (VSA) or transannular patch (TAP). Data from patients who underwent TOF repair between January 2016 and December 2019 were analyzed to compare the changes in the QRSd following intracardiac repair after VSA (Group 1) or TAP (Group 2). Among the 105 patients who underwent TOF surgical repair, 60 were included in the study (Group 1:30 vs. Group 2:30). Electrocardiograms (ECGs) were recorded pre- and post-surgery. The primary outcome was to compare the change in QRSd (ΔQRSd) before and after surgery between the two groups. The mean length of postoperative follow-up was 35.9 months in group 1 and 34.47 months in group 2. The mean [SD] difference in QRSd values (QRSd2 - QRSd1) was shorter in Group 1 (45.67 [22.79] ms) than in Group 2 (49.63 [23.76] ms); however, these differences were not statistically significant ( = 0.428). The PR interval was similar between the two groups in both preoperative and postoperative ECG. At the short-term follow-up, both surgical approaches (VSA and TAP) resulted in similar QRSd post-TOF repair. Studies with longer follow-up periods are required to evaluate the association of the surgical approach with prolongation of QRSd and mortality.

摘要

法洛四联症(TOF)修复术后的长期生存取决于多种因素,包括慢性右心室对手术的适应程度。QRS波时限(QRSd)是TOF修复术后危及生命的心律失常的重要决定因素。本单中心回顾性研究旨在评估采用保留肺动脉瓣方法(VSA)或跨环补片(TAP)进行TOF修复术后QRSd的变化。分析了2016年1月至2019年12月期间接受TOF修复的患者的数据,以比较VSA(第1组)或TAP(第2组)心内修复术后QRSd的变化。在105例行TOF手术修复的患者中,60例纳入研究(第1组:30例 vs. 第2组:30例)。术前和术后均记录心电图(ECG)。主要结局是比较两组手术前后QRSd的变化(ΔQRSd)。第1组术后平均随访时间为35.9个月,第2组为34.47个月。第1组QRSd值的平均[标准差]差异(QRSd2 - QRSd1)(45.67 [22.79] ms)短于第2组(49.63 [23.76] ms);然而,这些差异无统计学意义(P = 0.428)。术前和术后ECG两组的PR间期相似。在短期随访中,两种手术方法(VSA和TAP)在TOF修复术后的QRSd相似。需要进行更长随访期的研究来评估手术方法与QRSd延长和死亡率之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f657/11439427/aa54b420a19b/gcsp-2024-4-e202428-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f657/11439427/aa54b420a19b/gcsp-2024-4-e202428-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f657/11439427/aa54b420a19b/gcsp-2024-4-e202428-g001.jpg

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本文引用的文献

1
Arrhythmias in Repaired Tetralogy of Fallot: A Scientific Statement From the American Heart Association.《法洛四联症修复术后心律失常:美国心脏协会科学声明》
Circ Arrhythm Electrophysiol. 2022 Nov;15(11):e000084. doi: 10.1161/HAE.0000000000000084. Epub 2022 Oct 20.
2
What Is the Importance of Electrocardiography in the Routine Screening of Patients with Repaired Tetralogy of Fallot?心电图在法洛四联症修复术后患者常规筛查中的重要性是什么?
J Clin Med. 2021 Sep 22;10(19):4298. doi: 10.3390/jcm10194298.
3
Comparison of Long-term Outcomes of Valve-Sparing and Transannular Patch Procedures for Correction of Tetralogy of Fallot.
保留瓣叶和跨瓣环补片在法洛四联症矫治术中的长期疗效比较。
JAMA Netw Open. 2021 Jul 1;4(7):e2118141. doi: 10.1001/jamanetworkopen.2021.18141.
4
QRS Duration During Follow-Up of Tetralogy of Fallot: How Valuable is it? Analysis of ECG Changes in Relation to Pulmonary Valve Implantation.法洛四联症随访期间的 QRS 时限:它有多重要?分析与肺动脉瓣植入相关的心电图变化。
Pediatr Cardiol. 2021 Oct;42(7):1488-1495. doi: 10.1007/s00246-021-02632-y. Epub 2021 May 7.
5
Preventing Arrhythmic Death in Patients With Tetralogy of Fallot: JACC Review Topic of the Week.预防法洛四联症患者心律失常性死亡:美国心脏病学会评论专题周报。
J Am Coll Cardiol. 2021 Feb 16;77(6):761-771. doi: 10.1016/j.jacc.2020.12.021.
6
Current outcomes and treatment of tetralogy of Fallot.法洛四联症的当前治疗结果与治疗方法
F1000Res. 2019 Aug 29;8. doi: 10.12688/f1000research.17174.1. eCollection 2019.
7
Right ventricular function in patients with pulmonary regurgitation with versus without tetralogy of Fallot.伴有与不伴有法洛四联症的肺反流患者的右心室功能。
Am Heart J. 2019 Jul;213:8-17. doi: 10.1016/j.ahj.2019.03.012. Epub 2019 Apr 8.
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The effects of pulmonary valve replacement on QRS duration in repaired tetralogy of Fallot patients with pulmonary regurgitation.肺动脉瓣置换术对法洛四联症修复术后合并肺动脉反流患者QRS时限的影响。
J Electrocardiol. 2019 May-Jun;54:36-39. doi: 10.1016/j.jelectrocard.2019.02.010. Epub 2019 Feb 27.
9
Prognostic Significance of PR Interval Prolongation in Adult Patients With Total Correction of Tetralogy of Fallot.成人完全性法洛四联症矫正术后 PR 间期延长的预后意义。
Circ Arrhythm Electrophysiol. 2018 Nov;11(11):e006234. doi: 10.1161/CIRCEP.118.006234.
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