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Transformation of the Kidney into a Pathological Neuro-Immune-Endocrine Organ.

作者信息

Yamaguchi Manako, Almeida Lucas Ferreira de, Yamaguchi Hiroki, Liang Xiuyin, Smith Jason P, Medrano Silvia, Sequeira-Lopez Maria Luisa S, Gomez R Ariel

机构信息

Department of Pediatrics Child Health Research Center, University of Virginia School of Medicine, Charlottesville.

出版信息

Circ Res. 2024 Oct 25;135(10):1025-1027. doi: 10.1161/CIRCRESAHA.124.325305. Epub 2024 Oct 1.

DOI:10.1161/CIRCRESAHA.124.325305
PMID:39351666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11502242/
Abstract
摘要

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Renin Cells Drive Kidney Neurovascular Development and Arterial Remodeling when Renin Activity is Deficient.当肾素活性不足时,肾素细胞驱动肾脏神经血管发育和动脉重塑。
bioRxiv. 2025 Jul 11:2025.07.08.663706. doi: 10.1101/2025.07.08.663706.
2
APOL1 Dynamics in Diabetic Kidney Disease and Hypertension.载脂蛋白L1在糖尿病肾病和高血压中的动态变化
Biomolecules. 2025 Feb 1;15(2):205. doi: 10.3390/biom15020205.
3
Inhibition of Renin Release, a Crucial Event in Homeostasis, is Mediated by Coordinated Calcium Oscillations within Juxtaglomerular Cell Clusters.

本文引用的文献

1
Renin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics.肾素细胞发育:来自染色质可及性和单细胞转录组学的见解
Circ Res. 2023 Aug 4;133(4):369-371. doi: 10.1161/CIRCRESAHA.123.322827. Epub 2023 Jul 3.
2
Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans.肾素-血管紧张素系统的抑制会导致小鼠和人类肾小动脉的向心性肥大。
JCI Insight. 2021 Dec 22;6(24):e154337. doi: 10.1172/jci.insight.154337.
3
Targeting neural reflex circuits in immunity to treat kidney disease.
肾素释放的抑制是体内平衡中的一个关键事件,它由肾小球旁细胞簇内协调的钙振荡介导。
bioRxiv. 2025 Mar 21:2024.12.23.629519. doi: 10.1101/2024.12.23.629519.
靶向免疫中的神经反射回路以治疗肾脏疾病。
Nat Rev Nephrol. 2017 Nov;13(11):669-680. doi: 10.1038/nrneph.2017.132. Epub 2017 Oct 3.
4
Nerve Growth Factor: A Focus on Neuroscience and Therapy.神经生长因子:聚焦神经科学与治疗
Curr Neuropharmacol. 2015;13(3):294-303. doi: 10.2174/1570159x13666150403231920.
5
Sympathetic hyperinnervation and inflammatory cell NGF synthesis following myocardial infarction in rats.大鼠心肌梗死后的交感神经支配过度及炎症细胞神经生长因子合成
Brain Res. 2006 Dec 8;1124(1):142-54. doi: 10.1016/j.brainres.2006.09.054. Epub 2006 Nov 7.