Helios ENDO-Klinik, Holstenstraße 2, 22767, Hamburg, Germany.
Hospital Ortopedico de Goiânia, Avenida L nº470 Setor Aeroporto, Goiânia, 74075, Brazil.
Int Orthop. 2024 Dec;48(12):3049-3055. doi: 10.1007/s00264-024-06341-y. Epub 2024 Oct 1.
Total hip and knee arthroplasty in patients with previous history of periarticular surgery, such as osteosynthesis, can be surprisingly complex. This type of procedure is known as conversion arthroplasty (cTHA or cTKA) and has a higher risk of complications. The rates of unexpected positive cultures (UPC) and the risk of periprosthetic joint infection (PJI) compared to primary arthroplasty is unclear. The main purpose of this study was to evaluate rates of Unexpected Positive Cultures (UPC) in a series of conversion arthroplasty patients. The main questions to answer are: 1. Are the patients with conversion arthroplasties more susceptible to UPC than other causes of revision arthroplasties? 2. Are the conversion patients with UPC more susceptible to developing PJI?
This was a retrospective review of patients submitted to cTHA and cTKA from January 2012 to September 2018. Patients with history of previous infection or with missing intraoperative cultures were excluded. The UPC was defined as a single positive culture obtained during a procedure previously considered aseptic and PJI was defined according to the 2018 ICM criteria. After excluding 141 cases, 205 patients were analyzed, 160 hips and 45 knees.
Nine (4.4%) UPC were identified, five (3.1%) in the hip group and four (8,9%) in the knee group. Staphylococcal species were the most common isolated bacteria (n = 7, 77.7%). During the study period, four (1,9%) patients were diagnosed with PJI. Only one case had an UPC and a different germ was identified during revision arthroplasty workup.
While UPC are more prevalent in conversion knee arthroplasties compared to conversion hip arthroplasties, the rates are similar to those observed in revision arthroplasty for other indications. Importantly, the presence of a UPC in conversion arthroplasty does not appear to elevate the risk of subsequent periprosthetic joint infection, provided a thorough PJI workup has been conducted preoperatively. Therefore, in such cases, UPCs may be safely disregarded.
对于有既往关节周围手术史(如内固定)的患者,行全髋关节和全膝关节置换术可能会出乎意料地复杂。这种手术类型被称为翻修关节置换术(cTHA 或 cTKA),其并发症风险更高。与初次关节置换术相比,其未预料到的阳性培养(UPC)率和假体周围关节感染(PJI)风险尚不清楚。本研究的主要目的是评估一系列翻修关节置换术患者的未预料到的阳性培养(UPC)率。需要回答的主要问题是:1. 与其他原因的翻修关节置换术相比,接受翻修关节置换术的患者更容易发生 UPC 吗?2. 发生 UPC 的翻修患者更容易发生 PJI 吗?
这是一项回顾性研究,纳入了 2012 年 1 月至 2018 年 9 月期间行 cTHA 和 cTKA 的患者。排除了既往感染史或术中培养物缺失的患者。UPC 定义为之前被认为是无菌的手术中获得的单个阳性培养物,根据 2018 年 ICM 标准,PJI 定义为假体周围关节感染。排除 141 例后,分析了 205 例患者,包括 160 髋和 45 膝。
发现 9 例(4.4%)UPC,其中髋关节组 5 例(3.1%),膝关节组 4 例(8.9%)。葡萄球菌属是最常见的分离细菌(n=7,77.7%)。研究期间,4 例(1.9%)患者被诊断为 PJI。只有 1 例发生 UPC,在翻修关节置换术检查中发现了不同的细菌。
尽管与髋关节翻修相比,膝关节翻修中 UPC 更为常见,但发生率与其他适应证的翻修关节置换术相似。重要的是,在术前进行了彻底的 PJI 检查后,翻修关节置换术中出现 UPC 似乎并不会增加随后发生假体周围关节感染的风险。因此,在这种情况下,可以安全地忽略 UPC。