Yan Tao, Li Shuai, Yu Jianjun
Department of Urology, People's Hospital Affiliated to Ningbo University, 251 Baizhang East Road, Ningbo City, Zhejiang Province, 315040, China.
Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
BMC Surg. 2024 Oct 1;24(1):276. doi: 10.1186/s12893-024-02522-z.
To analyze the effect of transvesical laparoscopic radical prostatectomy (TVLRP) on sexual function and urinary continence.
The data of 72 patients diagnosed with low-risk and localized prostate cancer, who underwent treatment at our hospital between January 2017 and June 2022, were retrospectively analyzed. All these patients underwent TVLRP under general anesthesia. Their serum prostate-specific antigen (PSA), urinary continence and erectile function were statistically analyzed.
The operation went well with no intraoperative difficulties. The average surgical duration of 102 ± 22 min, coupled with the minimal intraoperative blood loss of 100 ± 32 mL, underscored the precision and efficacy of the surgical techniques employed. Following surgery, postoperative pathological assessments confirmed staging, revealing pT2a in 18 cases and pT2b in 54 cases, suggestive of localized tumors. Gleason scores ≤ 6 further indicated well-differentiated tumors, while consistently negative surgical margins affirmed the complete resection of tumors, reducing the likelihood of disease recurrence. Subsequent to the surgical intervention, the the average hospital stay was 13.94.1 days. A comprehensive 12-month follow-up revealed exceptionally high urinary continence rates, with 97.8% and 100% of patients achieving continence at 1 and 3 months postoperatively, respectively. Moreover, progressive improvement in erectile function recovery was observed, with recovery rates at 3, 6, and 12 months postoperatively reaching 82.2%, 88.4%, and 93.5%, respectively. There was no biochemical regression.
Treatment of low-risk and localized prostate cancer by TVLRP has a satisfactory urinary continence and recovery of erectile function after operation, less and complications and definite tumor-control effect.
分析经膀胱腹腔镜根治性前列腺切除术（TVLRP）对性功能和尿失禁的影响。
回顾性分析2017年1月至2022年6月在我院接受治疗的72例诊断为低危局限性前列腺癌患者的数据。所有这些患者均在全身麻醉下接受TVLRP。对他们的血清前列腺特异性抗原（PSA）、尿失禁和勃起功能进行统计学分析。
手术顺利，无术中困难。平均手术时间为102±22分钟，术中出血量极少，为100±32毫升，突出了所采用手术技术的精确性和有效性。术后病理评估证实了分期，18例为pT2a，54例为pT2b，提示为局限性肿瘤。Gleason评分≤6进一步表明肿瘤分化良好，而手术切缘始终为阴性，证实肿瘤已完全切除，降低了疾病复发的可能性。手术干预后，平均住院时间为13.9±4.1天。全面的12个月随访显示尿失禁率极高，分别有97.8%和100%的患者在术后1个月和3个月实现了控尿。此外，观察到勃起功能恢复有逐步改善，术后3个月、6个月和12个月的恢复率分别达到82.2%、88.4%和93.5%。无生化复发。
TVLRP治疗低危局限性前列腺癌术后尿失禁和勃起功能恢复良好，并发症少，肿瘤控制效果确切。
