Gu Jian-Jun, Tian Xiao-Chao, Bu Ji-Qiang, Chen Zi-Ying
Department of Cardiac Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
J Cardiothorac Surg. 2024 Oct 1;19(1):577. doi: 10.1186/s13019-024-03108-9.
To investigate the clinical effects and safety of the hybrid debranching technique for patients with acute Stanford type A aortic dissection (AD).
One hundred nine patients with acute Stanford type a AD were selected and divided into observation group and control group according to the different surgical methods. Fifty-five patients in the observation group were treated with hybrid debranching, and 54 patients in the control group were treated with Sun's operation. The operation duration, clamp time, cardiopulmonary bypass duration, volume of blood transfusion, ventilator application duration, duration of stay in the intensive care unit, aortic rupture, second thoracotomy due to hemorrhage, gastrointestinal hemorrhage, stroke, paraplegia, renal failure, and all-cause mortality were recorded. Postoperative follow-up was conducted. The number of cases that underwent follow-up and the number of cases with complete thrombosis of the false aneurysm cavity detected by computed tomography angiography (CTA) was recorded.
The surgical success rate was 100% in both groups, and there were no cases with unplanned secondary surgery. Compared with the control group, only the difference in the volume of blood transfusion was not significantly significant between the two groups (P = 0.052), while the rest of the observation indicators were significantly lower in the observation group than in the control group (P < 0.001 for all). The proportion of cases with complete thrombosis of the false aneurysm cavity was significantly higher in the observation group than in the control group at 3 and 6 months after surgery (P < 0.05).
In patients with acute Stanford type A AD involving the arch, the hybrid debranching technique was safe and effective. It was recommended for patients with advanced age and a high risk of intolerance to deep hypothermic circulatory arrest.
探讨杂交去分支技术治疗急性Stanford A型主动脉夹层(AD)患者的临床疗效及安全性。
选取109例急性Stanford A型AD患者,根据手术方式不同分为观察组和对照组。观察组55例采用杂交去分支技术治疗,对照组54例采用孙氏手术治疗。记录手术时间、主动脉阻断时间、体外循环时间、输血量、呼吸机使用时间、重症监护病房停留时间、主动脉破裂、因出血二次开胸、消化道出血、脑卒中、截瘫、肾衰竭及全因死亡率。进行术后随访,记录随访例数及计算机断层扫描血管造影(CTA)检测发现的假性动脉瘤腔完全血栓形成例数。
两组手术成功率均为100%,均无计划外二次手术病例。与对照组比较,两组仅输血量差异无统计学意义(P = 0.052),其余观察指标观察组均显著低于对照组(均P < 0.001)。术后3个月和6个月时,观察组假性动脉瘤腔完全血栓形成病例比例显著高于对照组(P < 0.05)。
对于累及主动脉弓的急性Stanford A型AD患者,杂交去分支技术安全有效。推荐用于高龄及对深低温停循环耐受性差的高危患者。