Huang Bing, Shi Jing, Feng Yingtong, Zhu Jianfu, Li Sen, Shan Ning, Xu Ying, Zhang Yujing
Department of Thoracic Cardiovascular Surgery, Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou, 221002, China.
Department of Medical Imaging, Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou, 221002, China.
J Cardiothorac Surg. 2024 Oct 1;19(1):565. doi: 10.1186/s13019-024-03095-x.
The purpose of this study was to compare the analgesic effects of intercostal nerve block (ICNB) and local anesthetic infiltration (LAI) on postoperative pain and recovery following thoracoscopic resection of pulmonary bullae.
A total of 160 patients undergoing thoracoscopic pulmonary bullae resection were randomly assigned to receive either ICNB (n = 80) or LAI (n = 80). An experienced anesthesiologist administered ultrasound guided ICNB at the T4 and T7 levels with 5 mL of 0.375% ropivacaine hydrochloride for the ICNB group. Instead, the LAI group received 10 mL of the same concentration of ropivacaine hydrochloride at the same concentration used for ICNB for infiltration anesthesia at the incision sites. Out of the initial cohort, 146 patients completed the study (ICNB group, n = 71; LAI group, n = 75). The collected data included preoperative clinical characteristics, visual analog scale (VAS) scores for pain at various time points post-surgery (6, 12, 24, 48, and 72 h). Additionally, the Quality of Recovery-15 (QoR-15) questionnaire was administered 24 h after surgery, and sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI).
No significant differences were found in drainage volume, use of additional analgesics, duration of chest tube placement, or hospital stay between the two groups. However, the ICNB group had significantly lower VAS scores and QoR-15 scores 24 h postoperatively (p < 0.05), indicating better pain management and recovery. The ICNB group also reported better sleep quality, as reflected by lower PSQI scores.
ICNB provides superior analgesia compared to LAI after thoracoscopic resection of pulmonary bullae, significantly improving postoperative recovery.
本研究旨在比较肋间神经阻滞(ICNB)和局部麻醉药浸润(LAI)对胸腔镜下肺大疱切除术后疼痛及恢复情况的镇痛效果。
总共160例接受胸腔镜下肺大疱切除术的患者被随机分配接受ICNB(n = 80)或LAI(n = 80)。一位经验丰富的麻醉医生在T4和T7水平为ICNB组实施超声引导下的ICNB,使用5毫升0.375%的盐酸罗哌卡因。相反,LAI组在切口部位接受10毫升相同浓度的盐酸罗哌卡因用于浸润麻醉,该浓度与ICNB所用浓度相同。在初始队列中,146例患者完成了研究(ICNB组,n = 71;LAI组,n = 75)。收集的数据包括术前临床特征、术后不同时间点(6、12、24、48和72小时)的疼痛视觉模拟量表(VAS)评分。此外,术后24小时进行恢复质量-15(QoR-15)问卷调查,并使用匹兹堡睡眠质量指数(PSQI)评估睡眠质量。
两组在引流量、额外镇痛药的使用、胸管留置时间或住院时间方面未发现显著差异。然而,ICNB组术后24小时的VAS评分和QoR-15评分显著更低(p < 0.05),表明疼痛管理和恢复情况更好。ICNB组的睡眠质量也更好,PSQI评分更低体现了这一点。
与胸腔镜下肺大疱切除术后的LAI相比,ICNB提供了更好的镇痛效果,显著改善了术后恢复情况。