Richardson Andrea, Muhammad Sheheryar, McSwain Chelsea, Tran Haijing
Holy Cross Hospital, Silver Spring, MD, USA.
Hosp Pharm. 2024 Oct;59(5):584-587. doi: 10.1177/00185787241238309. Epub 2024 Mar 28.
Many infectious diseases are diagnosed in emergency departments (ED) and patients are prescribed antimicrobial therapy. Results from cultures typically take a few days to become finalized. Following up on these results is necessary when medication changes are indicated due to results that show bacteria are resistant to the prescribed antibiotics. Involving pharmacists in assessing the culture and sensitivity results, and making interventions when needed, is an innovative way to ensure that patients receive appropriate antimicrobial therapy based on the culture and sensitivity data. This study analyzed the impact of pharmacist involvement in the ED's post-discharge positive culture review process on ED re-visits and hospitalizations. : This single-center, pre- and post-implementation study examined the impact of pharmacist involvement in the post-ED visit culture review process on ED re-visits and hospitalizations. Positive microbiological results included documented growth from urine, skin and soft tissue, throat, blood, or stool cultures. Patients included in the study were of 18 years of age or older and had a positive culture result post ED-discharge. Patients were excluded from the study if they were admitted to the hospital or transferred to another facility. The primary outcomes included ED re-visits within 7 days and hospital readmissions within 30 days for the same condition. The secondary outcomes were percentage of pharmacist interventions accepted and types of pharmacist interventions implemented. : A total of 141 patients were included in the study, with 65 in the pre-implementation group and 76 in the post-implementation group. The primary outcome of ED re-visits within 7 days for the same condition occurred in 11 (17%) patients in the pre-implementation group and 5 (7%) patients in the post-implementation group ( = .0454). The primary outcome of hospitalizations within 30 days for the same condition occurred in 5 (8%) patients in the pre-implementation group and 1 (1%) patient in the post-implementation group ( = .0137). Seventeen (94%) out of the 18 pharmacist interventions were accepted and implemented. The intervention types implemented were to recommend to: change antibiotic (35%), not initiate antibiotic (24%), initiate antibiotic (24%), and continue antibiotic (18%). : Pharmacist involvement in the ED post-discharge positive culture review process showed a decrease in ED re-visits and hospitalizations for the same condition.
许多传染病在急诊科被诊断出来,患者会接受抗菌治疗。培养结果通常需要几天才能最终确定。当培养结果显示细菌对所开抗生素耐药而需要更改用药时,跟进这些结果是必要的。让药剂师参与评估培养和药敏结果,并在需要时进行干预,是确保患者根据培养和药敏数据接受适当抗菌治疗的一种创新方式。本研究分析了药剂师参与急诊科出院后阳性培养复查过程对急诊复诊和住院的影响。:这项单中心、实施前后的研究考察了药剂师参与急诊后访视培养复查过程对急诊复诊和住院的影响。微生物学阳性结果包括尿液、皮肤和软组织、咽喉、血液或粪便培养中有记录的细菌生长。纳入研究的患者年龄在18岁及以上,且急诊出院后培养结果为阳性。如果患者入院或转至其他机构,则被排除在研究之外。主要结局包括同一病情在7天内的急诊复诊和30天内的再次住院。次要结局是药剂师干预被接受的百分比和实施的药剂师干预类型。:共有141名患者纳入研究,实施前组65名,实施后组76名。同一病情在7天内的急诊复诊这一主要结局在实施前组有11名(17%)患者出现,在实施后组有5名(7%)患者出现(P = 0.0454)。同一病情在30天内的住院这一主要结局在实施前组有5名(8%)患者出现,在实施后组有1名(1%)患者出现(P = 0.0137)。18项药剂师干预中有17项(94%)被接受并实施。实施的干预类型包括建议:更换抗生素(35%)、不开始使用抗生素(24%)、开始使用抗生素(24%)和继续使用抗生素(18%)。:药剂师参与急诊科出院后阳性培养复查过程显示,同一病情的急诊复诊和住院次数有所减少。