蝙蝠葛碱：药理活性综述。
Dauricine: Review of Pharmacological Activity.
作者信息
Chen Ke-Qian, Wang Shu-Zhi, Lei Hai-Bo, Liu Xiang
机构信息
Department of Clinical Pharmacy, Xiangtan Central Hospital, Xiangtan, 411100, People's Republic of China.
Institute of Pharmacy and Pharmacology, School of Pharmaceutical Sciences, Hengyang Medical School, University of South China, Hengyang, 421001, People's Republic of China.
出版信息
Drug Des Devel Ther. 2024 Sep 27;18:4371-4385. doi: 10.2147/DDDT.S471352. eCollection 2024.
BACKGROUND
Dauricine is an important natural organic compound in , which often has significant biological activity.
PURPOSE
The purpose of this review is to systemically summarize and discuss the pharmacological activity and underlying mechanisms of dauricine in recent years.
METHODS
Web of Science (121 articles) and PubMed databases (97 articles) were used to search for articles related to "dauricine" published from 2000 to 2024. Meanwhile, we classified the pharmacological activity of dauricine by screening these articles.
RESULTS
Emerging evidence suggests that dauricine possesses numerous pharmacological activities, including neuroprotection, anti-cancer, anti-arrhythmia, anti-inflammatory and anti-diabetes.
CONCLUSION
Dauricine has a potential value in the treatment of many diseases. We hope that this review will contribute to therapeutic development and future studies of dauricine.
背景
蝙蝠葛碱是一种重要的天然有机化合物，常具有显著的生物活性。
目的
本综述旨在系统总结和讨论近年来蝙蝠葛碱的药理活性及其潜在机制。
方法
利用科学网（121篇文章）和PubMed数据库（97篇文章）检索2000年至2024年发表的与“蝙蝠葛碱”相关的文章。同时，通过筛选这些文章对蝙蝠葛碱的药理活性进行分类。
结果
新出现的证据表明，蝙蝠葛碱具有多种药理活性，包括神经保护、抗癌、抗心律失常、抗炎和抗糖尿病。
结论
蝙蝠葛碱在多种疾病的治疗中具有潜在价值。我们希望本综述将有助于蝙蝠葛碱的治疗开发和未来研究。
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