铜催化4-吲哚甲醇与氮丙啶的(4+3)环加成反应：氮杂环庚烷并吲哚的立体选择性合成
Copper-catalyzed (4+3)-cycloaddition of 4-indolylcarbinols with aziridines: stereoselective synthesis of azepinoindoles.
作者信息
Kar Subhradeep, Maharana Prabhat Kumar, Maity Swagata, Trivedi Vishal, Punniyamurthy Tharmalingam
机构信息
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, India.
出版信息
Chem Commun (Camb). 2024 Oct 15;60(83):12008-12011. doi: 10.1039/d4cc03544e.
Copper(I)-catalyzed (4+3)-cycloaddition of 4-indolylcarbinols with aziridines has been accomplished to furnish azepinoindoles. The chirality transfer, substrate scope, functional group tolerance, natural product modification and tandem C-C/C-N bond formation are the important practical features.
实现了铜（I）催化的4-吲哚甲醇与氮丙啶的（4+3）环加成反应，以制备氮杂环庚并吲哚。手性转移、底物范围、官能团耐受性、天然产物修饰以及串联C-C/C-N键的形成是重要的实际特征。
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