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用于监测肌肉缺血的低成本便携式近红外光谱仪的评估

Evaluation of a low-cost portable NIRS device for monitoring muscle ischemia.

作者信息

Marrero-García Ramsés, Cruz-Tabares Yaiza, Gonzalez-Cava Jose M, Méndez-Pérez Juan Albino, Reboso-Morales José Antonio

机构信息

Critical Care Department and Pain Unit, Clinic Hospital, Barcelona, Spain.

Anesthesia, Resuscitation and Pain Unit, Cruces Hospital, 48903, Baracaldo, Spain.

出版信息

J Clin Monit Comput. 2025 Apr;39(2):459-468. doi: 10.1007/s10877-024-01226-2. Epub 2024 Oct 2.

Abstract

The main objective of this study is to evaluate the low-cost, open-source HEGduino device as a tissue oximetry monitor to advance the research of somatic NIRS monitoring. Specifically, this study analyzes the use of this portable functional NIRS system for detecting the cessation of blood flow due to vascular occlusion in an upper limb. 19 healthy patients aged between 25 and 50 were recruited and monitored using HEGduino device. Participants underwent a vascular occlusion test on one forearm. Raw values collected by HEGduino as well as the processed variables derived from the measurements were registered. Additional variables to characterize the signal noise during the tests were also recorded. The results of the data distribution curves for all the subjects in the study accurately detected the physiological events associated with transient tissue ischemia. The statistical analysis of the recorded data showed that the difference between the baseline values recorded by the red led (RED) and its normalized minimum variable was always different from zero (p < 0.014). Furthermore, the difference between the normalized baseline values recorded by the infrared led (IR) and the corresponding normalized minimum value was also different from zero (p < 0.001). The R-squared coefficient of determination for the noise variables considered in this study on the normalized RED and IR values was 0.08 and 0.105, respectively. The study confirms the potential of HEGduino system to detect an interruption of the blood flow by means of variations in regional tissue oxygen saturation. This study demonstrates the potential of the HEGduino device as a monitoring alternative to advance the study of the applicability of NIRS in muscle tissue oximetry.

摘要

本研究的主要目的是评估低成本、开源的HEGduino设备作为组织血氧饱和度监测仪,以推进体部近红外光谱(NIRS)监测的研究。具体而言,本研究分析了这种便携式功能近红外光谱系统用于检测上肢血管闭塞导致的血流停止的情况。招募了19名年龄在25至50岁之间的健康患者,并使用HEGduino设备进行监测。参与者在一侧前臂进行了血管闭塞测试。记录了HEGduino收集的原始值以及从测量中得出的处理变量。还记录了用于表征测试期间信号噪声的其他变量。研究中所有受试者的数据分布曲线结果准确地检测到了与短暂组织缺血相关的生理事件。对记录数据的统计分析表明,红色发光二极管(RED)记录的基线值与其归一化最小值变量之间的差异始终不为零(p < 0.014)。此外,红外发光二极管(IR)记录的归一化基线值与相应归一化最小值之间的差异也不为零(p < 0.001)。本研究中考虑的噪声变量在归一化RED和IR值上的决定系数R平方分别为0.08和0.105。该研究证实了HEGduino系统通过区域组织氧饱和度变化检测血流中断的潜力。本研究证明了HEGduino设备作为一种监测替代方案的潜力,可推进近红外光谱在肌肉组织血氧饱和度测定中适用性的研究。

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