Kumar Shah Bipesh, Prasad Yadav Shankar, Nagpal Dheeraj, Pokhrel Naveen, Lamichhane Samiksha
Department of Pediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
Department of Radiodiagnosis, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.
JNMA J Nepal Med Assoc. 2024 Apr 30;62(273):336-338. doi: 10.31729/jnma.8579.
Hypereosinophilic syndrome with respiratory distress and multiorgan involvement is not so common in children. It is essential to identify this entity based on clinical, laboratory, and imaging features. Corticosteroids should be instituted at the earliest to stabilize the patient and prevent organ damage. Tropical infections are a common secondary cause in children warranting the administration of Diethylcarbamazine. We present a case of an adolescent male in respiratory distress with marked eosinophilia and organs involving the lungs (pulmonary infiltrates with effusion), heart (pericardial effusion), and abdomen (ascites with infiltrates in the liver) which was managed with steroids and anthelmintics. The case highlights the importance of identifying patients with Hypereosinophilic syndrome in pursuing thorough evaluation and commencing therapy.
伴有呼吸窘迫和多器官受累的高嗜酸性粒细胞综合征在儿童中并不常见。基于临床、实验室和影像学特征来识别这一病症至关重要。应尽早使用皮质类固醇来稳定患者病情并预防器官损伤。热带感染是儿童常见的继发性病因，需要使用乙胺嗪进行治疗。我们报告一例青少年男性病例，该患者出现呼吸窘迫，伴有明显的嗜酸性粒细胞增多，累及肺部（肺部浸润伴胸腔积液）、心脏（心包积液）和腹部（腹水伴肝脏浸润），通过类固醇和驱虫药进行治疗。该病例凸显了识别高嗜酸性粒细胞综合征患者以进行全面评估并开始治疗的重要性。
