Kavtaradze V G, Iosava K V, Andriadze N A, Kurashvili R B, Dundua M G
Kardiologiia. 1985 Sep;25(9):14-7.
Nitroglycerin was drip-infused for 24 hours to 35 patients with acute myocardial infarction. Thirty-three patients were taken as controls. Intergroup comparisons were made of the patterns of precordial cartograms from 35 leads and serial measurements of plasma MB CPK activity. The treatment was shown to reduce significantly the activity of MB CPK and total ST elevation, the effect being particularly pronounced with the drug administered within the first 6 hours of the attack. It was also shown that 24-hour intravenous nitroglycerin infusion produced a significant decrease in the end diastolic pressure of the pulmonary artery that occurred by the 15th minute and persisted till the end of the administration.
对35例急性心肌梗死患者静脉滴注硝酸甘油24小时。将33例患者作为对照。对35导联胸前心电图模式和血浆肌酸磷酸激酶同工酶MB（MB CPK）活性的系列测量结果进行组间比较。结果显示，该治疗可显著降低MB CPK活性和总ST段抬高，在发作后最初6小时内给药效果尤为明显。还显示，静脉滴注硝酸甘油24小时可使肺动脉舒张压在第15分钟时显著降低，并持续至给药结束。
