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Brain age estimation: premise, promise, and problems.

作者信息

Perron Jarrad, Ko Ji Hyun

机构信息

Graduate Program in Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB, Canada (Perron J, Ko JH).

PrairieNeuro Research Centre, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB, Canada (Perron J, Ko JH).

出版信息

Neural Regen Res. 2025 Aug 1;20(8):2313-2314. doi: 10.4103/NRR.NRR-D-24-00388. Epub 2024 Jul 29.

DOI:10.4103/NRR.NRR-D-24-00388
PMID:39359085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11759032/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a899/11759032/e3f3d1e0c6dc/NRR-20-2313-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a899/11759032/e3f3d1e0c6dc/NRR-20-2313-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a899/11759032/e3f3d1e0c6dc/NRR-20-2313-g001.jpg

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本文引用的文献

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MRI or F-FDG PET for Brain Age Gap Estimation: Links to Cognition, Pathology, and Alzheimer Disease Progression.MRI 或 F-FDG PET 用于估计脑龄差距：与认知、病理学和阿尔茨海默病进展的关联。
J Nucl Med. 2024 Jan 2;65(1):147-155. doi: 10.2967/jnumed.123.265931.
3
Analysis of Costs for Imaging-Assisted Pharmaceutical Intervention in Alzheimer's Disease with Lecanemab: Snapshot of the First 3 Years.
基于仑卡奈单抗的阿尔茨海默病影像辅助药物干预的成本分析：头 3 年的快照。
J Alzheimers Dis. 2023;96(3):1305-1315. doi: 10.3233/JAD-230633.
4
Cocaine Destroys Gray Matter Brain Cells and Accelerates Brain Aging.可卡因会破坏灰质脑细胞并加速大脑衰老。
Biology (Basel). 2023 May 21;12(5):752. doi: 10.3390/biology12050752.
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Alzheimer's Disease-Related Metabolic Pattern in Diverse Forms of Neurodegenerative Diseases.多种神经退行性疾病中与阿尔茨海默病相关的代谢模式
Diagnostics (Basel). 2021 Nov 1;11(11):2023. doi: 10.3390/diagnostics11112023.
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DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging.DNA 甲基化和慢性炎症的蛋白质标志物及其与大脑和认知衰老的关联。
Neurology. 2021 Dec 7;97(23):e2340-e2352. doi: 10.1212/WNL.0000000000012997. Epub 2021 Nov 17.
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Ten Years of as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?作为脑老化神经影像生物标志物的十年：我们获得了哪些见解？
Front Neurol. 2019 Aug 14;10:789. doi: 10.3389/fneur.2019.00789. eCollection 2019.
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Inflammatory markers and imaging patterns of advanced brain aging in the general population.一般人群中大脑老化进展的炎症标志物和影像学模式。
Brain Imaging Behav. 2020 Aug;14(4):1108-1117. doi: 10.1007/s11682-019-00058-y.
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Machine learning identified an Alzheimer's disease-related FDG-PET pattern which is also expressed in Lewy body dementia and Parkinson's disease dementia.机器学习识别出一种与阿尔茨海默病相关的 FDG-PET 模式，这种模式也存在于路易体痴呆和帕金森病痴呆中。
Sci Rep. 2018 Sep 5;8(1):13236. doi: 10.1038/s41598-018-31653-6.
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