Rao Raghavendra
Department of Dermatology, Venereology and Leprology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Indian Dermatol Online J. 2024 Aug 30;15(5):739-748. doi: 10.4103/idoj.idoj_755_23. eCollection 2024 Sep-Oct.
Autoimmune blistering diseases (AIBDs) are a type of dermatosis with antibodies produced against various structural proteins of the epidermis or dermoepidermal junction. AIBDs are broadly divided into intraepidermal and subepidermal types. Apart from the common AIBDs, there is an array of uncommon AIBDs.
To discuss uncommon variants of AIBDs so that the readers are updated about them.
In this review, we have discussed uncommon and unusual variants like pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus, induced pemphigus, IgG/IgA pemphigus, oral lichenoid pigmentation in pemphigus, pemphigus acanthoma, and follicular pemphigus. Rarer variants of the pemphigoid group of disorders include anti-laminin 332 pemphigoid, mixed linear IgA/IgG pemphigoid, anti-p200 pemphigoid, Brunsting-Perry pemphigoid, IgM pemphigoid, granular C3 pemphigoid, anti-p105 pemphigoid, ORF-induced anti-laminin 332 pemphigoid, and acral purpura in dermatitis herpetiformis.
This review will help in early diagnosis and treatment of uncommon and unusual variants of AIBDs.
自身免疫性大疱性疾病（AIBDs）是一类皮肤病，机体产生针对表皮或真皮表皮交界处各种结构蛋白的抗体。AIBDs大致分为表皮内型和表皮下型。除了常见的AIBDs外，还有一系列不常见的AIBDs。
讨论AIBDs的不常见变异型，以便让读者了解这些疾病。
在本综述中，我们讨论了不常见和特殊的变异型，如疱疹样天疱疮、IgA天疱疮、副肿瘤性天疱疮、诱发性天疱疮、IgG/IgA天疱疮、天疱疮中的口腔苔藓样色素沉着、棘细胞瘤性天疱疮和毛囊性天疱疮。类天疱疮疾病组中较罕见的变异型包括抗层粘连蛋白332类天疱疮、混合性线性IgA/IgG类天疱疮、抗p200类天疱疮、布伦斯廷-佩里类天疱疮、IgM类天疱疮、颗粒状C3类天疱疮、抗p105类天疱疮、ORF诱导的抗层粘连蛋白332类天疱疮以及疱疹样皮炎中的肢端紫癜。
本综述将有助于AIBDs不常见和特殊变异型的早期诊断和治疗。
