Patrick Bailey, Beck Anne-Taylor, Casterline Benjamin W, Martin Kari L
Department of Dermatology, University of Missouri, Columbia, USA.
Cureus. 2024 Sep 1;16(9):e68401. doi: 10.7759/cureus.68401. eCollection 2024 Sep.
Postmenopausal craniofacial hyperhidrosis describes a unique subset of primary focal hyperhidrosis in menopausal woman. This condition can be challenging to treat and may require multiple treatment modalities before patients express satisfaction with the results. Current treatment options for craniofacial hyperhidrosis include oral antimuscarinic agents, topical aluminum chloride powder, and botulinum toxin injections. We present the case of a 68-year-old female with craniofacial hyperhidrosis who did not respond to topical agents and did not tolerate an oral antimuscarinic agent. The patient was successfully treated with 100 units of onabotulinum toxin A along the forehead, frontal hairline, and periauricular scalp and reported significant improvement in symptoms and quality of life as a result. We review the literature describing targeted intradermal injection of botulinum neurotoxin as an alternative to medical therapy for craniofacial hyperhidrosis.
绝经后颅面部多汗症是绝经后女性原发性局灶性多汗症的一个独特亚型。这种病症治疗起来颇具挑战性，在患者对治疗结果表示满意之前，可能需要多种治疗方式。目前颅面部多汗症的治疗选择包括口服抗胆碱能药物、外用氯化铝粉末和肉毒毒素注射。我们报告一例68岁患有颅面部多汗症的女性病例，该患者对局部用药无反应，且无法耐受口服抗胆碱能药物。该患者通过在前额、额发际线和耳周头皮处注射100单位的A型肉毒毒素得到成功治疗，症状和生活质量均有显著改善。我们回顾了将肉毒神经毒素靶向皮内注射作为颅面部多汗症药物治疗替代方法的相关文献。
