Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hong Kong Med J. 2024 Oct;30(5):362-370. doi: 10.12809/hkmj219738. Epub 2024 Oct 3.
This cross-sectional survey research investigated mental health symptoms and quality of life among Chinese parents and their children with eczema at a paediatric dermatology clinic in Hong Kong from November 2018 to October 2020.
Health-related quality of life, eczema severity, and mental health among children with eczema, as well as their parents' mental health, were studied using the Children's Dermatology Life Quality Index (CDLQI), Infants' Dermatitis Quality of Life Index (IDQOL), Nottingham Eczema Severity Score (NESS), Patient-Oriented Eczema Measure (POEM), and the Chinese version of the 21-item Depression, Anxiety, and Stress Scales (DASS-21).
In total, 432 children and 380 parents were recruited. Eczema severity (NESS and POEM) and health-related quality of life (CDLQI) were significantly positively associated with parental and child depression, anxiety, and stress levels according to the DASS-21, regardless of sex (children: r=0.28- 0.72, P<0.001 to 0.007; parents: r=0.20-0.52, P<0.001 to 0.034). Maternal depression was marginally positively associated with increased anxiety in boys with eczema (r=0.311; P=0.045). Younger parents had higher risk of developing more anxiety and stress compared with the older parents (adjusted odds ratio [aOR]=-0.342, P=0.014 and aOR=-0.395, P=0.019, respectively). Depression level of parents with primary to secondary education was 58% higher than their counterparts with post-secondary education or above (aOR=-1.579; P=0.007).
Depression, anxiety, and stress among children with eczema and their parents were associated with eczema severity and impaired quality of life in those children. These findings regarding impaired mental health in children with eczema and their parents highlight the need to include mental well-being and psychosocial outcomes in future studies and clinical practice.
本横断面研究调查了 2018 年 11 月至 2020 年 10 月期间在香港一家儿科皮肤科诊所就诊的中国父母及其患有湿疹的孩子的心理健康症状和生活质量。
采用儿童皮肤病生活质量指数（CDLQI）、婴儿皮炎生活质量指数（IDQOL）、诺丁汉湿疹严重程度评分（NESS）、患者导向的湿疹量表（POEM）和中文版 21 项抑郁、焦虑和压力量表（DASS-21）对湿疹患儿及其父母的健康相关生活质量、湿疹严重程度和心理健康进行研究。
共纳入 432 名儿童和 380 名家长。无论性别如何（儿童：r=0.28-0.72，P<0.001 至 0.007；父母：r=0.20-0.52，P<0.001 至 0.034），湿疹严重程度（NESS 和 POEM）和健康相关生活质量（CDLQI）与父母和儿童的抑郁、焦虑和压力水平呈显著正相关。母亲的抑郁与湿疹男孩的焦虑程度呈轻微正相关（r=0.311；P=0.045）。与年龄较大的父母相比，年轻父母患焦虑症和压力的风险更高（调整后比值比[aOR]=-0.342，P=0.014 和 aOR=-0.395，P=0.019）。具有小学及以下学历的父母的抑郁水平比具有中学及以上学历的父母高 58%（aOR=-1.579；P=0.007）。
湿疹患儿及其父母的抑郁、焦虑和压力与湿疹严重程度和患儿生活质量受损有关。这些关于湿疹患儿及其父母心理健康受损的发现强调了需要在未来的研究和临床实践中纳入心理健康和社会心理结局。
