Medley G, Anderson R M
Trans R Soc Trop Med Hyg. 1985;79(4):532-4. doi: 10.1016/0035-9203(85)90087-2.
An analysis is presented of autopsy data collected by Cheever in 1968 on the association between Schistosoma mansoni worm burdens and faecal egg counts. Significant negative relationships are found between the number of eggs/worm pair/g faeces and both the number of worm pairs and the total number of worms. A general, non-linear, statistical routine is shown to be the most practical method of fitting non-linear models to the observed density-dependent fecundity relationship. The conceptual and practical implications of density-dependence are discussed in the context of epidemiological field studies and chemotherapy programmes.
本文对Cheever于1968年收集的关于曼氏血吸虫虫负荷与粪便虫卵计数之间关联的尸检数据进行了分析。发现每克粪便中虫卵/虫对的数量与虫对数量及虫的总数之间均存在显著的负相关关系。结果表明，一种通用的非线性统计程序是将非线性模型拟合到观察到的密度依赖性繁殖力关系的最实用方法。在流行病学现场研究和化疗项目的背景下，讨论了密度依赖性的概念和实际意义。
