Gastroenterology Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Division of Gastroenterology and Hepatology, Veterans Affairs Palo Alto Healthcare System, Stanford University School of Medicine, 3801 Miranda Avenue, GI-111, Palo Alto, CA 94304, USA.
Clin Liver Dis. 2024 Nov;28(4):589-600. doi: 10.1016/j.cld.2024.06.001. Epub 2024 Jul 23.
Alcohol-associated liver disease (ALD) was already on the rise globally when the advent of coronavirus disease 2019 further accelerated this trend. ALD has emerged as the leading cause for liver transplantation in the United States. The pandemic has not only intensified the prevalence of ALD but has also highlighted significant disparities in its impact, particularly, among young adults and women. This review aims to dissect the complex landscape of ALD, focusing on gender, race, and emerging risk factors in the context of the current global health crisis.
当 2019 冠状病毒病（COVID-19）的出现进一步加速这一趋势时，酒精相关性肝病（ALD）在全球已经呈上升趋势。ALD 已成为美国肝移植的主要原因。大流行不仅加剧了 ALD 的流行，而且还突出显示了其影响方面的巨大差异，特别是在年轻人和妇女中。本综述旨在剖析 ALD 的复杂情况，重点关注当前全球卫生危机背景下的性别、种族和新出现的危险因素。
