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破译内脏本能:从分子到大脑,揭开食物选择之谜的科学探索。

Deciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind.

机构信息

Laboratory of Gut Brain Neurobiology, Duke University, Durham, North Carolina 27710; USA;

Department of Medicine, Duke University, Durham, North Carolina 27710; USA.

出版信息

Genes Dev. 2024 Oct 16;38(17-20):798-801. doi: 10.1101/gad.352279.124.

DOI:10.1101/gad.352279.124
PMID:39362782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11535160/
Abstract

The study of biological mechanisms, while crucial, cannot fully explain complex phenomena like the instinct to eat. The mind-body connection, as exemplified by the concept of "voodoo death," highlights the profound influence of belief and cultural context on physiology. Indigenous knowledge systems further emphasize the interconnectedness of humans with their environment. Recent discoveries in gut-brain communication reveal the intricate neural circuits that drive our visceral desires, but a holistic approach that integrates both physiological mechanisms and the subjective experience of life, informed by diverse cultural perspectives, will be essential to truly understand what it means to be alive.

摘要

虽然对生物机制的研究至关重要,但它无法完全解释像进食本能这样的复杂现象。身心联系,如“巫毒死亡”概念所示,突出了信仰和文化背景对生理学的深远影响。本土知识体系进一步强调了人类与其环境的相互联系。最近在肠道-大脑通讯方面的发现揭示了驱动我们内脏欲望的复杂神经回路,但要真正理解生命的意义,还需要一种将生理机制和生活的主观体验相结合的整体方法,并借鉴多种文化视角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a4/11535160/0959e489d693/798f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a4/11535160/0959e489d693/798f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a4/11535160/0959e489d693/798f01.jpg

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