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冲击波治疗女性型脱发患者的毛发再生。

Shock Waves for Hair Growth and Regeneration in Patients With Female Pattern Hair Loss.

机构信息

Aesthetic Medicine, Elite Laser Clinic, Madrid, Spain.

出版信息

Skin Res Technol. 2024 Oct;30(10):e70064. doi: 10.1111/srt.70064.

DOI:10.1111/srt.70064
PMID:39362836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11449676/
Abstract

BACKGROUND

Female pattern hair loss (FPHL) is women's most common form of alopecia. The study aimed to evaluate the efficacy of extracorporeal shock waves for hair growth and regeneration in women with FPHL.

METHODS

A prospective single-center noncontrolled study was conducted in patients with FPHL who underwent eight treatment sessions with C-Actor, a shock wave applicator. Outcome measures included total hair count, number of follicular units (FUs)-single FUs, double FUs, triple and bigger FUs-the average thickness, cumulative hair thickness, and changes in the Derived Sinclair scale, assessed with Tricholab (Fotofinder System). Patients completed a survey to assess their subjective perceptions of hair improvement regarding softness, hair loss, quality, and volume.

RESULTS

Twenty women were included with a mean age of 43 (SD = 5.65). The mean increase in total hair count was 8.9% (p < 0.00001), in number of FUs 4.6% (p = 0.00031), in number of triple and bigger FUs 18.4% (p = 0.0004), in cumulative hair thickness 8.0% (p < 0.00001), with a decrease of 5.7% in mean Derived Sinclair scale value by 2.2-2.1 (p < 0.0001). After 3 months, 85% of patients perceived improvement in hair volume.

CONCLUSION

Extracorporeal shock waves for hair growth and capillary regeneration in women with FPHL showed statistically significant outcomes, and all patients reported an improvement in hair characteristics.

摘要

背景

女性型脱发(FPHL)是女性最常见的脱发形式。本研究旨在评估体外冲击波治疗女性 FPHL 患者毛发生长和再生的疗效。

方法

对接受 C-Actor(一种冲击波应用器)治疗的 FPHL 患者进行了一项前瞻性单中心非对照研究。共 20 名女性患者接受了 8 次治疗。主要结局指标包括总发量、单个毛囊单位(FU)-单 FU、双 FU、三 FU 及更大 FU-平均厚度、累积发量以及 Derived Sinclair 量表评分的变化,采用 Tricholab(Fotofinder System)进行评估。患者完成了一份关于毛发改善的主观感知的调查问卷,包括柔软度、脱发、质量和体积。

结果

20 名女性患者的平均年龄为 43 岁(SD=5.65)。总发量增加了 8.9%(p<0.00001),FU 数量增加了 4.6%(p=0.00031),三 FU 及更大 FU 数量增加了 18.4%(p=0.0004),累积发量增加了 8.0%(p<0.00001),平均 Derived Sinclair 量表评分由 2.2 下降至 2.1(p<0.0001)。治疗 3 个月后,85%的患者认为发量有改善。

结论

体外冲击波治疗 FPHL 患者的毛发生长和毛细血管再生显示出统计学上的显著效果,所有患者均报告毛发特征得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/1713bd12862d/SRT-30-e70064-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/53e0f8228d7e/SRT-30-e70064-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/10b2ad0c2673/SRT-30-e70064-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/5fd6b211f730/SRT-30-e70064-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/1713bd12862d/SRT-30-e70064-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/53e0f8228d7e/SRT-30-e70064-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/10b2ad0c2673/SRT-30-e70064-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/5fd6b211f730/SRT-30-e70064-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2940/11449676/1713bd12862d/SRT-30-e70064-g003.jpg

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Stem Cells Cloning. 2023 Nov 20;16:77-89. doi: 10.2147/SCCAA.S432179. eCollection 2023.
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Female Pattern Hair Loss: An Overview with Focus on the Genetics.女性型脱发:综述及其遗传学重点。
Genes (Basel). 2023 Jun 23;14(7):1326. doi: 10.3390/genes14071326.
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Systematic review of exosome treatment in hair restoration: Preliminary evidence, safety, and future directions.外泌体治疗毛发再生的系统评价:初步证据、安全性和未来方向。
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Molecular Mechanisms Underlying the Pain-Relieving Effects of Extracorporeal Shock Wave Therapy: A Focus on Fascia Nociceptors.体外冲击波疗法止痛作用的分子机制:聚焦筋膜伤害感受器
Life (Basel). 2022 May 17;12(5):743. doi: 10.3390/life12050743.
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Dermatol Surg. 2022 Jul 1;48(7):737-740. doi: 10.1097/DSS.0000000000003472. Epub 2022 Apr 25.
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