Rewald E, Estevez M E, Sen L
Am J Pediatr Hematol Oncol. 1985 Winter;7(4):331-5.
A case is reported of a 12-year-old girl with a benign course of a lymphocytosis through years associated with splenomegaly. The lymphocytes simultaneously expressed a monoclonal B-cell phenotype of IgM-kappa and a mature T-antigen using the monoclonal OKT1 antibody. Due to her stable condition, no treatment was required. The immunological results suggest the possibility of an early childhood B-cell chronic lymphoid leukemia.
报告了一例12岁女孩，多年来淋巴细胞增多症病程呈良性，伴有脾肿大。淋巴细胞同时表达IgM-κ单克隆B细胞表型，并使用单克隆OKT1抗体表达成熟T抗原。由于她病情稳定，无需治疗。免疫学结果提示可能为儿童期早期B细胞慢性淋巴细胞白血病。
