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应对颌面部放线菌病的挑战:一例诊断过程曲折且需多学科协作的病例

Navigating Challenges in Cervicofacial Actinomycosis: A Case of Diagnostic Persistence and Multidisciplinary Collaboration.

作者信息

Sony Sandra, Sistla Sarath C, Rao Mrudula

机构信息

General Practice, ASHWINI (Association for Health Welfare in the Nilgiris) - Gudalur Adivasi Hospital, Gudalur, IND.

General Surgery, Vivekananda Memorial Hospital, Sargur, IND.

出版信息

Cureus. 2024 Sep 3;16(9):e68533. doi: 10.7759/cureus.68533. eCollection 2024 Sep.

DOI:10.7759/cureus.68533
PMID:39364511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11448761/
Abstract

Actinomycosis is a rare, chronic bacterial infection caused by species, characterized by granulomatous inflammation, abscesses, and sinus tracts. It primarily affects the cervicofacial region and often mimics other conditions such as malignancies or tuberculosis, complicating early diagnosis and treatment. This case report details an 18-year-old male with no known comorbidities, who presented with a two-week history of facial swelling, trismus, and discharging fistulas following an insect bite. The delay in seeking medical attention was due to initial symptom subsidence and challenges in accessing care. Diagnostic difficulties arose from inconclusive pus cultures and the lack of specialist resources at our facility. An incisional biopsy and subsequent histopathological examination revealed basophilic Gram-positive, non-acid fast filamentous bacteria and the Splendore-Hoeppli phenomenon, ultimately confirming actinomycosis. This case highlights the necessity of including actinomycosis in the differential diagnosis of facial infections and demonstrates the value of a multidisciplinary approach in managing complex cases with diagnostic and therapeutic challenges.

摘要

放线菌病是一种由放线菌属引起的罕见慢性细菌感染,其特征为肉芽肿性炎症、脓肿和窦道。它主要累及颈面部区域,常与其他疾病如恶性肿瘤或结核病相似,导致早期诊断和治疗复杂化。本病例报告详细介绍了一名18岁无已知合并症的男性,他在被昆虫叮咬后出现了两周的面部肿胀、牙关紧闭和引流瘘管病史。延迟就医是由于最初症状消退以及就医困难。诊断困难源于脓液培养结果不明确以及我们机构缺乏专业资源。切开活检及随后的组织病理学检查发现了嗜碱性革兰氏阳性、抗酸不染色的丝状细菌以及Splendore-Hoeppli现象,最终确诊为放线菌病。本病例强调了在面部感染的鉴别诊断中纳入放线菌病的必要性,并展示了多学科方法在处理具有诊断和治疗挑战的复杂病例中的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/13cf2a047100/cureus-0016-00000068533-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/ea37f639d8f9/cureus-0016-00000068533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/2069e8d60719/cureus-0016-00000068533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/89fd61617c23/cureus-0016-00000068533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/cef9c45c22ca/cureus-0016-00000068533-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/13cf2a047100/cureus-0016-00000068533-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/ea37f639d8f9/cureus-0016-00000068533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/2069e8d60719/cureus-0016-00000068533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/89fd61617c23/cureus-0016-00000068533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/cef9c45c22ca/cureus-0016-00000068533-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/311f/11448761/13cf2a047100/cureus-0016-00000068533-i05.jpg

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本文引用的文献

1
Cervical Facial Actinomycosis Complicated by Bacteremia After 30 Years of Dental Neglect: Successful Treatment With Ceftriaxone and Metronidazole.因30年忽视口腔卫生导致的颈部面部放线菌病并发菌血症:头孢曲松和甲硝唑治疗成功
Cureus. 2024 Jan 6;16(1):e51734. doi: 10.7759/cureus.51734. eCollection 2024 Jan.
2
Actinomycotic osteomyelitis of the maxilla in a female patient: A rare case report with the review of the literature.一名女性患者上颌骨放线菌性骨髓炎:罕见病例报告并文献复习
Dent Med Probl. 2024 Mar-Apr;61(2):301-306. doi: 10.17219/dmp/127639.
3
Surgical debridement as a treatment strategy for cervicofacial actinomycosis-Literature review and case report.
手术清创术作为颈面部放线菌病的一种治疗策略——文献综述与病例报告
Int J Surg Case Rep. 2020;73:22-26. doi: 10.1016/j.ijscr.2020.06.079. Epub 2020 Jun 22.
4
Diagnosis and Management of Cervicofacial Actinomycosis: Lessons from Two Distinct Clinical Cases.颈面部放线菌病的诊断与管理:来自两例不同临床病例的经验教训。
Antibiotics (Basel). 2020 Mar 25;9(4):139. doi: 10.3390/antibiotics9040139.
5
Microbiological and Clinical Aspects of Cervicofacial Infections: An Overview.颌面部感染的微生物学与临床概况:综述
Dent J (Basel). 2019 Sep 1;7(3):85. doi: 10.3390/dj7030085.
6
Splendore-Hoeppli phenomenon.斯-何二氏现象
J Oral Maxillofac Pathol. 2018 May-Aug;22(2):161-162. doi: 10.4103/jomfp.JOMFP_79_18.
7
Aerobic Actinomycetes of Clinical Significance.临床意义上的需氧放线菌。
Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.DMIH2-0021-2015.
8
Actinomycosis: etiology, clinical features, diagnosis, treatment, and management.放线菌病:病因、临床特征、诊断、治疗和管理。
Infect Drug Resist. 2014 Jul 5;7:183-97. doi: 10.2147/IDR.S39601. eCollection 2014.
9
Imaging of actinomycosis in various organs: a comprehensive review.各器官放线菌病影像学表现:全面综述。
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