Addanki Sunaina, Patel Lisa, Patel Krina, Khanna Deepesh
Neurology/Cardiology, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Cureus. 2024 Sep 2;16(9):e68485. doi: 10.7759/cureus.68485. eCollection 2024 Sep.
Hidradenitis suppurativa (HS) is an inflammatory disease affecting the pilosebaceous skin units and is linked to several autoimmune conditions. An area of exploration includes the connection between hyperthyroidism and HS. This study aims to investigate and establish the relationship between HS and hyperthyroidism.
The relationship between hyperthyroidism and HS was evaluated using data from the National Institute of Health (NIH) All of Us Researcher Program. A cross-sectional study was performed to assess the prevalence of HS in individuals with and without a history of hyperthyroidism matched by age ranges and health surveys. Relative risk and significance were determined by using standard statistical methods.
A total of 407,333 patients were matched by health surveys and age ranges in the control and experimental groups. Among patients with a history of hyperthyroidism, the prevalence of HS was 1.40% compared to 0.38% in the control group. This difference was statistically significant (p < 0.0001 with an OR = 3.717, 95% CI 3.038-4.548).
This study demonstrates a statistically significant correlation between hyperthyroidism and increased prevalence of HS. These results justify the need for further research regarding hyperthyroidism's role in HS and the potential screening tools and lifestyle management techniques that may be prevalent for both conditions.
化脓性汗腺炎（HS）是一种影响毛囊皮脂腺皮肤单位的炎症性疾病，与多种自身免疫性疾病有关。一个探索领域包括甲状腺功能亢进与HS之间的联系。本研究旨在调查并确定HS与甲状腺功能亢进之间的关系。
利用美国国立卫生研究院（NIH）“我们所有人”研究项目的数据评估甲状腺功能亢进与HS之间的关系。进行了一项横断面研究，以评估有和没有甲状腺功能亢进病史的个体中HS的患病率，这些个体按年龄范围和健康调查进行匹配。使用标准统计方法确定相对风险和显著性。
通过健康调查和年龄范围，在对照组和实验组中总共匹配了407,333名患者。在有甲状腺功能亢进病史的患者中，HS的患病率为1.40%，而对照组为0.38%。这种差异具有统计学意义（p<0.0001，OR=3.717，95%CI 3.038 - 4.548）。
本研究表明甲状腺功能亢进与HS患病率增加之间存在统计学上的显著相关性。这些结果证明有必要进一步研究甲状腺功能亢进在HS中的作用以及可能适用于这两种情况的潜在筛查工具和生活方式管理技术。
