Department of Obstetrics and Gynaecology, ASUFC, Ospedale Santa Maria della Misericordia, Udine, Italy.
Obstetrics and Gynaecology, Department of Medical Area (DAME), University of Udine, Udine, Italy.
Gynecol Endocrinol. 2024 Dec;40(1):2411727. doi: 10.1080/09513590.2024.2411727. Epub 2024 Oct 4.
Pregnancy is a critical period marked by intricate physiological changes and maintaining maternal and fetal well-being is paramount. Inositols, a group of naturally occurring sugar alcohols, have gained attention for their potential benefits during pregnancy. This abstract provides a comprehensive review of the current literature on using inositols, primarily myo-inositol (MI) and D-chiro-inositol (DCI) in pregnancy. Inositols are crucial in cellular signal transduction and insulin sensitivity, making them integral to various physiological processes. Several studies suggest that inositols may contribute to preventing and managing gestational diabetes mellitus (GDM). MI, in particular, has shown promise in improving insulin sensitivity and mitigating insulin resistance, thereby influencing glucose metabolism. As our understanding of inositol's role in pregnancy deepens, it may emerge as a valuable supplement to enhance maternal and fetal health outcomes.
妊娠是一个关键时期，其特点是复杂的生理变化，维持母婴健康至关重要。肌醇，一组天然存在的糖醇，因其在妊娠期间的潜在益处而受到关注。本文对目前关于在妊娠中使用肌醇（主要是肌醇和 D-手性肌醇）的文献进行了全面综述。肌醇在细胞信号转导和胰岛素敏感性中起着重要作用，是各种生理过程的重要组成部分。几项研究表明，肌醇可能有助于预防和治疗妊娠期糖尿病（GDM）。特别是肌醇，已显示出改善胰岛素敏感性和减轻胰岛素抵抗的潜力，从而影响葡萄糖代谢。随着我们对肌醇在妊娠中作用的理解加深，它可能成为一种有价值的补充剂，以提高母婴健康结局。
