Department of Medicine and Aging, School of Medicine and Health Sciences, "G. d'Annunzio" University, Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University, Chieti-Pescara, 66100 Chieti, Italy.
Nutrients. 2022 Apr 8;14(8):1543. doi: 10.3390/nu14081543.
There is growing interest in the potential role of different stereoisomers of inositol or their combination as well as probiotics supplementation in healthy glucose metabolism during pregnancy and in promoting offspring health. The aim of this review is to clarify the effects of several inositol and probiotics-based supplements in the prevention and treatment of gestational diabetes (GDM). Moreover, we will discuss the epigenetic aspects and their short- and long-term effects in response to probiotic intervention as well as the possible implications of these findings in guiding appropriate supplementation regimens in pregnancy.
人们对不同的肌醇立体异构体或其组合以及益生菌补充剂在妊娠期间健康葡萄糖代谢和促进后代健康中的潜在作用越来越感兴趣。本综述的目的是阐明几种基于肌醇和益生菌的补充剂在预防和治疗妊娠期糖尿病（GDM）中的作用。此外，我们将讨论表观遗传方面及其对益生菌干预的短期和长期影响，以及这些发现对指导妊娠期间适当补充方案的可能影响。
