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多布斯诉杰克逊案前后的在线药物流产直接向患者提供服务。

Online Medication Abortion Direct-to-Patient Fulfillment Before and After the Dobbs v Jackson Decision.

机构信息

Ibis Reproductive Health, Cambridge, Massachusetts.

Honeybee Health, Culver City, California.

出版信息

JAMA Netw Open. 2024 Oct 1;7(10):e2434675. doi: 10.1001/jamanetworkopen.2024.34675.

Abstract

IMPORTANCE

Online pharmacies have emerged as stakeholders in abortion care since the US Food and Drug Administration (FDA) relaxed in-person dispensing requirements in 2020. The role of online pharmacies in dispensing abortion medications following the Dobbs v Jackson Women's Health Organization decision on June 24, 2022, is understudied.

OBJECTIVE

To describe medication abortion prescription fulfillment patterns for 1 online pharmacy 1 year before and after the Dobbs v Jackson decision, considering patient, prescriber, and state policy characteristics.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study assesses deidentified medication abortion prescription fulfilment data from 1 online pharmacy. Prescribers sent prescription requests to the online pharmacy, which dispensed abortion medications to patients by mail. The study sample included prescription requests fulfilled by the online pharmacy between June 20, 2021, and June 24, 2023, for patients aged at least 18 years who received the combined medication abortion regimen. Data were analyzed from July 2023 to July 2024.

EXPOSURES

The US Supreme Court Dobbs v Jackson decision on June 24, 2022.

MAIN OUTCOMES AND MEASURES

Patient and prescriber characteristics are described, including patient age, state to which the prescription was sent, medications prescribed, and prescribing prescriber's clinic care modality (in-person only, hybrid [in-person and virtual], and virtual only). States were grouped according to the Guttmacher Institute classification of policy support for abortion (most or very supportive, somewhat supportive, and somewhat restrictive). Fulfillment trends were disaggregated by prescriber modality and state policy environment; 2 states with similar telehealth but differing coverage policies (Illinois and Colorado) were compared.

RESULTS

The dataset included 87 942 observations. Most prescriptions were sent to individuals younger than 30 years (57.1%), with a mean (SD) age of 28.7 (6.4) years. Throughout the study period, the greatest volume of prescription requests came from states with most or very supportive policies and from prescribers at virtual-only platforms. More prescriptions were sent in the year after Dobbs v Jackson (daily mean [SD], 88.5 [47.2] prescriptions in March 2022 vs 201.5 [97.5] prescriptions in March 2023) with fulfillment spikes following the Dobbs v Jackson leak on May 2, 2022, and decision on June 24, 2022. State policy contexts mirrored the overall trends, while prescriber modality trends were unique, with a big spike in fulfillment at 12 weeks after the Dobbs v Jackson decision for hybrid clinics compared with in-person-only clinics and telehealth-only platforms, which saw their largest spikes in mean daily prescription fulfillment the week immediately after Dobbs v Jackson. Illinois and Colorado had similar fulfillment trends, with spikes immediately following the Dobbs v Jackson decision and overall higher fulfillment after Dobbs v Jackson, with a daily mean (SD) of 10.5 (7.0) prescriptions in Illinois and 8.8 (5.7) prescriptions in Colorado in March 2022 versus 26.6 (13.6) prescriptions in Illinois and 16.7 (10.1) prescriptions in Colorado in March 2023.

CONCLUSIONS AND RELEVANCE

These findings illustrate the increasingly critical role online pharmacies play in direct-to-patient abortion care provision in the US and the strong linkages between virtual-only prescribers and online pharmacies. These findings suggest that barriers to accessing online pharmacies for abortion care should be removed.

摘要

重要性

自美国食品和药物管理局(FDA)在 2020 年放宽了亲自配药的要求以来,在线药店已成为堕胎护理的利益相关者。2022 年 6 月 24 日多布斯诉杰克逊妇女健康组织案之后,在线药店在配药堕胎药物方面的作用尚未得到充分研究。

目的

描述一家在线药店在多布斯诉杰克逊案前后一年的药物流产处方配药模式,同时考虑患者、处方医生和州政策特征。

设计、地点和参与者:本横断面研究评估了一家在线药店的匿名药物流产处方配药数据。处方医生向在线药店发送处方请求,然后在线药店通过邮件向患者发放堕胎药物。研究样本包括 2021 年 6 月 20 日至 2023 年 6 月 24 日期间由在线药店完成的至少 18 岁患者接受联合药物流产方案的处方请求。数据分析于 2023 年 7 月至 2024 年 7 月进行。

暴露因素

美国最高法院多布斯诉杰克逊案于 2022 年 6 月 24 日作出裁决。

主要结果和测量

描述了患者和处方医生的特征,包括患者年龄、处方发送的州、开处方的药物以及处方医生的诊所治疗模式(仅亲自就诊、混合模式[亲自和虚拟]和仅虚拟)。根据古特马赫研究所对堕胎政策支持程度的分类(最支持或非常支持、有些支持和有些限制)对各州进行分组。按处方医生模式和州政策环境对履行趋势进行了细分;比较了两个具有类似远程医疗但覆盖政策不同的州(伊利诺伊州和科罗拉多州)。

结果

数据集包括 87942 个观察结果。大多数处方都是发给年龄在 30 岁以下的人(57.1%),平均年龄(标准差)为 28.7(6.4)岁。在整个研究期间,最大数量的处方请求来自最支持或非常支持政策的州,以及仅虚拟平台的处方医生。在多布斯诉杰克逊案之后,处方数量增加(每日平均[标准差],2022 年 3 月为 88.5[47.2]份,而 2023 年 3 月为 201.5[97.5]份),在 2022 年 5 月 2 日多布斯诉杰克逊案泄露和 2022 年 6 月 24 日裁决之后出现了履行高峰。州政策环境反映了总体趋势,而处方医生模式趋势则较为独特,与仅亲自就诊诊所和远程医疗仅平台相比,混合诊所的履行高峰出现在多布斯诉杰克逊案判决后 12 周,而仅亲自就诊诊所和远程医疗仅平台的履行高峰则出现在多布斯诉杰克逊案判决后一周。伊利诺伊州和科罗拉多州的履行趋势相似,在多布斯诉杰克逊案之后都出现了高峰,而且多布斯诉杰克逊案之后的履行情况总体上有所增加,2022 年 3 月,伊利诺伊州的日平均(标准差)为 10.5(7.0)份,科罗拉多州为 8.8(5.7)份,而 2023 年 3 月,伊利诺伊州为 26.6(13.6)份,科罗拉多州为 16.7(10.1)份。

结论和相关性

这些发现说明了在线药店在美国直接向患者提供堕胎护理方面的作用日益重要,以及虚拟仅处方医生和在线药店之间的紧密联系。这些发现表明,应该消除获取堕胎护理的在线药店的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03e/11452820/5d5becd1075f/jamanetwopen-e2434675-g001.jpg

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