时机就是一切：m6A 何时被沉积？
Timing is everything: When is m6A deposited?
机构信息
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
出版信息
Mol Cell. 2024 Oct 3;84(19):3572-3573. doi: 10.1016/j.molcel.2024.09.012.
PMID:39366343
Abstract
In this issue of Molecular Cell, Tang et al. suggest that m6A deposition is predominantly post-transcriptional. They further propose that nuclear dwell time dictates the post-transcriptional accumulation of m6A. These findings have important implications for m6A biogenesis and function.
摘要
在本期《分子细胞》中，Tang 等人提出 m6A 的沉积主要发生在转录后阶段。他们进一步提出核停留时间决定了 m6A 的转录后积累。这些发现对 m6A 的生物发生和功能具有重要意义。
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