绒猴和人滋养层干细胞的常见和罕见发现。

Common and uncommon findings in marmoset and human trophoblast stem cells.

机构信息

Department of Trophoblast Research, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 862-0973, Japan.

Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.

出版信息

Cell Stem Cell. 2024 Oct 3;31(10):1387-1388. doi: 10.1016/j.stem.2024.07.008.

DOI:10.1016/j.stem.2024.07.008

PMID:39366357

Abstract

In this issue of Cell Stem Cell, Siriwardena et al. analyze peri- and post-implantation marmoset trophoblast development in detail and establish marmoset trophoblast stem cell (TSC) lines from pluripotent stem cells (PSCs). Comparative analysis of marmoset and human TSCs provides insights into species-specific implantation and placentation strategies.

摘要

在本期《Cell Stem Cell》中，Siriwardena 等人详细分析了围植入期和植入后狨猴滋养层的发育情况，并从多能干细胞中建立了狨猴滋养层干细胞（TSC）系。对狨猴和人 TSC 的比较分析为物种特异性植入和胎盘形成策略提供了深入了解。