Saffati Gal, Seyan Zheyar, Rendon Daniela Orozco, Almuhaideb Mana, Hinojosa-Gonzalez David E, Kronstedt Shane, Khera Mohit
Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, United States.
Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX 79430, United States.
Sex Med Rev. 2025 Jan 31;13(1):11-19. doi: 10.1093/sxmrev/qeae066.
Erectile dysfunction (ED), affecting around 52% of men aged 40-70, is a significant marker of overall health and a potential warning sign of multiple conditions like cardiovascular diseases (CVDs), diabetes, and mental health disorders. Recognizing and addressing ED through a holistic approach involving nutrition, physical activity, sleep, and stress management can improve both erectile and overall health outcomes.
To provide a narrative review of the available literature on the relationship between ED and overall health, elaborate on the possible mechanisms explaining this association, and discuss the effects of lifestyle on ED.
A search of the medical literature was carried out in PubMed and Medline, focusing on original research and systematic reviews of original research on ED and overall health.
Due to shared pathophysiological mechanisms like endothelial dysfunction, ED is a significant indicator of overall health, particularly related to CVD and diabetes mellitus. Multiple studies have shown that ED frequently precedes cardiovascular events and is associated with increased cardiovascular risk, especially in younger men and those with diabetes. It also has a profound, bidirectional relationship with mental health conditions like depression and anxiety, creating a vicious cycle where each exacerbates the other. The four health pillars of nutrition, physical activity, sleep, and stress management play significant roles in erectile function and overall sexual health.
ED is not just a condition affecting sexual function but a critical indicator of broader health issues. By adopting an integrative approach that combines nutrition, physical activity, sleep, and stress management, healthcare providers can offer holistic and effective management strategies for this condition.
勃起功能障碍(ED)影响着约52%的40至70岁男性,是整体健康的重要标志,也是心血管疾病(CVD)、糖尿病和心理健康障碍等多种疾病的潜在警示信号。通过采用包括营养、体育活动、睡眠和压力管理在内的整体方法来认识和解决ED问题,可改善勃起功能和整体健康状况。
对有关ED与整体健康关系的现有文献进行叙述性综述,阐述解释这种关联的可能机制,并讨论生活方式对ED的影响。
在PubMed和Medline上检索医学文献,重点关注关于ED与整体健康的原创研究和原创研究的系统评价。
由于存在内皮功能障碍等共同的病理生理机制,ED是整体健康的重要指标,尤其与CVD和糖尿病相关。多项研究表明,ED常常先于心血管事件出现,并与心血管风险增加有关,特别是在年轻男性和糖尿病患者中。它还与抑郁症和焦虑症等心理健康状况存在深刻的双向关系,形成一种恶性循环,即二者相互加剧。营养、体育活动、睡眠和压力管理这四个健康支柱在勃起功能和整体性健康中发挥着重要作用。
ED不仅是一种影响性功能的疾病,更是更广泛健康问题的关键指标。通过采用结合营养、体育活动、睡眠和压力管理的综合方法,医疗保健提供者可为这种疾病提供全面有效的管理策略。