Laboratory of 3D Imaging and Analytical Methods, Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Viničná 7, 128 00, Prague 2, Czech Republic.
Department of Histology and Embryology, Third Faculty of Medicine, Charles University, Ruská 2411, 100 00, Prague 10, Czech Republic.
Sci Rep. 2024 Oct 4;14(1):23131. doi: 10.1038/s41598-024-73077-5.
We aimed to describe facial directional asymmetry (DA) in individuals with different manifestations of laterality. Due to the overlap between brain and face development, a relationship between the manifestation of brain laterality and DA is hypothesised. These findings could clarify the relationship between the brain and facial phenotype and help to plan facial or oral motor rehabilitation. The DA of 163 healthy individuals was assessed by two complementary 3D methods: landmark and polygonal surface analysis using colour-coded maps. Handedness was assessed using the Edinburgh Handedness Inventory, while chewing side and eye preferences were self-reported. The results showed a similar DA pattern regardless of sex and laterality (the right-sided protrusion of the forehead, nose, lips, and chin) and a slightly curved C-shape of the midline in landmark analysis. A relationship between lateralized behaviours and DA was found only in males, in females the DA pattern was more homogenous. Right-handed individuals and right-side chewers showed a protrusion of the right hemiface. Males, left-handed and left-side chewers, manifested a protrusion of the left lateral hemiface. We suggest that these specific differences in males may be due to their typically higher level of brain asymmetry. No apparent relationship was found between eyedness and DA.
我们旨在描述具有不同偏侧性表现的个体的面部定向不对称（DA）。由于大脑和面部发育之间存在重叠，因此假设大脑偏侧性的表现与 DA 之间存在关系。这些发现可以阐明大脑和面部表型之间的关系，并有助于规划面部或口腔运动康复。通过两种互补的 3D 方法评估了 163 名健康个体的 DA：使用彩色编码图的地标和多边形表面分析。使用爱丁堡手性量表评估手性，自我报告咀嚼侧和眼偏好。结果表明，无论性别和偏侧性如何（额部、鼻子、嘴唇和下巴的右侧突出），地标分析中都存在相似的 DA 模式，中线呈略微弯曲的 C 形。仅在男性中发现偏侧性行为与 DA 之间存在关系，而在女性中，DA 模式更为均匀。右利手和右侧咀嚼者表现出右半脸的突出。男性、左撇子和左侧咀嚼者表现出左侧外侧半脸的突出。我们认为，男性中出现这些特定差异可能是由于他们大脑不对称程度通常较高。未发现眼偏斜与 DA 之间存在明显关系。
