Kozlova G S, Benemanskiĭ V V, Buziun A F, Portnoĭ A A
Farmakol Toksikol. 1985 Nov-Dec;48(6):76-80.
The cardiovascular system was examined in acute, subacute and chronic intoxications with nitroglycerin. It was revealed that morphofunctional alterations were uniform in nature, being more demonstrable in chronic exposure during 6 months. Myocardial alterations were characterized by disturbed hemodynamics, dystrophy, focal myocarditis, changes in the activity of enzymes, and changes in the electrocardio- and rheovasographic readings. Prolonged intoxication produced more profound and stable alterations.
对硝酸甘油急性、亚急性和慢性中毒情况下的心血管系统进行了检查。结果显示,形态功能改变本质上是一致的,在6个月的慢性接触中表现得更为明显。心肌改变的特征为血液动力学紊乱、营养不良、局灶性心肌炎、酶活性变化以及心电图和血流图读数改变。长期中毒会导致更深刻和稳定的改变。