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[硝酸甘油中毒时心血管系统的形态功能变化]

[Morphofunctional changes in the cardiovascular system in nitroglycerin poisoning].

作者信息

Kozlova G S, Benemanskiĭ V V, Buziun A F, Portnoĭ A A

出版信息

Farmakol Toksikol. 1985 Nov-Dec;48(6):76-80.

PMID:3936731
Abstract

The cardiovascular system was examined in acute, subacute and chronic intoxications with nitroglycerin. It was revealed that morphofunctional alterations were uniform in nature, being more demonstrable in chronic exposure during 6 months. Myocardial alterations were characterized by disturbed hemodynamics, dystrophy, focal myocarditis, changes in the activity of enzymes, and changes in the electrocardio- and rheovasographic readings. Prolonged intoxication produced more profound and stable alterations.

摘要

对硝酸甘油急性、亚急性和慢性中毒情况下的心血管系统进行了检查。结果显示,形态功能改变本质上是一致的,在6个月的慢性接触中表现得更为明显。心肌改变的特征为血液动力学紊乱、营养不良、局灶性心肌炎、酶活性变化以及心电图和血流图读数改变。长期中毒会导致更深刻和稳定的改变。

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