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一项关于自杀未遂短程干预方案(ASSIP)对近期自杀未遂者有效性的研究方案:一项随机对照试验。

A study protocol of the effectiveness of the Attempted Suicide Short Intervention Program (ASSIP) for recent suicide attempters: a randomized controlled trial.

机构信息

Department of Clinical Sciences, Lund, Psychiatry, Lund University, SE-221 84, Lund, Sweden.

Office of Psychiatry and Habilitation, Region Skåne, SE-221 85, Lund, Sweden.

出版信息

BMC Psychiatry. 2024 Oct 4;24(1):655. doi: 10.1186/s12888-024-06109-z.

Abstract

BACKGROUND

Given the limited research focusing on psychotherapeutic interventions for suicide attempters, it is noteworthy that the Attempted Suicide Short Intervention Program (ASSIP) has demonstrated promising results in previous studies. In this investigation, we aim to evaluate the effectiveness of ASSIP across diverse healthcare settings, outlining the study design and planned evaluation.

METHODS

Using a Randomized Controlled Trial (RCT) design with four assessment points (baseline, 3, 12- and 24-month follow-up), we aim to assess the effect of the 3-session psychotherapeutic intervention and hereafter brief contact via structured letters during 2 years in a clinical sample of recent suicide attempters (suicide attempts within three months before inclusion). Participants are randomly assigned to one of two groups; treatment as usual plus ASSIP or the control condition, treatment as usual. Assessments include measures of suicidal intent, coping, symptoms of depression, quality of life, self-stigma, and sick leave. The primary outcome is suicide attempt(s) within 3, 12, and 24 months and the secondary outcome is suicidal ideation within the same time frames after study inclusion.

DISCUSSION

Findings from this study will provide novel insights regarding the effects of ASSIP on not only subsequent suicidal behavior but also other outcomes including self-stigma, quality of life, social network, sick leave, and symptoms of depression.

TRIAL REGISTRATION

The trial was registered at ClinicalTrial.gov NCT04746261 on 2020-10-15.

摘要

背景

鉴于针对自杀未遂者的心理治疗干预措施的研究有限,值得注意的是,自杀未遂短期干预计划(ASSIP)在之前的研究中已显示出良好的效果。在这项研究中,我们旨在评估 ASSIP 在不同医疗保健环境中的有效性,概述研究设计和计划评估。

方法

我们采用随机对照试验(RCT)设计,设置四个评估点(基线、3 个月、12 个月和 24 个月随访),旨在评估为期 3 节的心理治疗干预措施的效果,以及此后在 2 年内通过结构化信件进行的简短联系,对最近自杀未遂者(纳入前 3 个月内自杀未遂)的临床样本进行评估。参与者被随机分配到两组之一:ASSIP 联合常规治疗或常规治疗对照组。评估包括自杀意念、应对方式、抑郁症状、生活质量、自我污名、病假等指标。主要结局是在 3、12 和 24 个月内发生自杀未遂,次要结局是在研究纳入后的相同时间框架内出现自杀意念。

讨论

该研究的结果将为 ASSIP 不仅对随后的自杀行为,而且对自我污名、生活质量、社交网络、病假和抑郁症状等其他结局的影响提供新的见解。

试验注册

该试验于 2020 年 10 月 15 日在 ClinicalTrials.gov 上注册,编号为 NCT04746261。

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