Department of Pediatrics, NewYork-Presbyterian Morgan Stanley Children's Hospital, Columbia University Irving Medical Center, New York, New York, USA.
Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, Perelman School of Medicine at UPenn, Philadelphia, Pennsylvania, USA.
J Pediatric Infect Dis Soc. 2024 Nov 27;13(11):594-598. doi: 10.1093/jpids/piae099.
To determine if healthcare-associated (HA)-respiratory syncytial virus (RSV) is associated with worse outcomes, this multicenter cohort study studied 26 children with HA-RSV and 78 matched non-HA-RSV patients of whom 58% and 55%, respectively, had ≥2 comorbidities. Overall, 39% of HA-RSV versus 18% of non-HA-RSV patients required respiratory support escalation (adjusted odds ratio (aOR) 5.1, CI95 1.4, 19.1).
为了确定与医疗保健相关的(HA)-呼吸道合胞病毒(RSV)是否与更差的结局相关,这项多中心队列研究纳入了 26 例 HA-RSV 患儿和 78 例匹配的非 HA-RSV 患儿,其中分别有 58%和 55%的患儿存在≥2 种合并症。总体而言,需要呼吸支持升级的 HA-RSV 患儿比例为 39%,而非 HA-RSV 患儿为 18%(调整后的优势比(aOR)为 5.1,95%CI95 为 1.4,19.1)。