Hernandez Emanuel, Rosado Amaris, Johnson Eleanor, Mundell Ben, Davila Victor, Fong Zhi Ven, Jorge Irving
University of Puerto Rico School of Medicine, San Juan, PR, United States.
Department of General Surgery, Mayo Clinic Arizona, Phoenix, AZ, United States.
J Gastrointest Surg. 2024 Dec;28(12):2048-2054. doi: 10.1016/j.gassur.2024.09.028. Epub 2024 Oct 3.
Radiation exposure (RE) causes dose-dependent deleterious effects, and efforts should be made to decrease patient exposure to ionizing radiation. Patients with choledocholithiasis are commonly exposed to ionizing radiation as fluoroscopy-guided interventions including minimally invasive common bile duct (CBD) exploration (MICBDE) and endoscopic retrograde cholangiopancreatography (ERCP) are the preferred treatment modalities for CBD stone clearance. However, RE and fluoroscopy times (FTs) have not been compared between these 2 treatment modalities. Thus, this study aimed to compare FT and RE between MICBDE and ERCP in patients with choledocholithiasis.
This is a retrospective analysis of a prospectively maintained database of a single surgeon performing MICBDE at an academic referral center between May 2021 and June 2023 compared with a retrospective analysis of all ERCPs performed between January 2020 and February 2021. Patient demographics, procedural details, fluoroscopic details, and postoperative outcomes were compared between the MICBDE and ERCP. The study was conducted as a single institution academic referral center located in the American Southwest. A total of 109 patients with choledocholithiasis were divided into 2 groups. A total of 53 (48.62%) patients underwent ERCP, and 56 (51.38%) patients underwent MICBDE. Inclusion criterion was all patients presenting with choledocholithiasis and subsequently undergoing ERCP or MICBDE. Patients who underwent ERCP for non-choledocholithiasis-related reasons were excluded. Primary outcomes include FT measured in minutes and RE measured in milligray (mGy). Secondary outcomes were successful clearance of the CBD, complications, procedural time, and reinterventions.
A significant difference (P < .001) between FTs was identified between ERCP (3.1 min) and MICBDE (1.54 min). Median RE doses between the ERCP group (38 mGy) and the MICBDE group (38.41 mGy) were not statistically different (P = .88). Technical success of CBD clearance was similar in both groups (91% in the MICBDE group vs 93% in ERCP group; P = .711).
Advantages of MICBDE over ERCP include the treatment of choledocholithiasis at the time of cholecystectomy, which reduces the risk of additional anesthesia episodes and introduces the potential for shorter hospital length of stay. This study showed that MICDBE had lower FT than had ERCP, and comparable RE. Given the advantages of MICBDE, it should be strongly considered at the time of laparoscopic cholecystectomy.
辐射暴露(RE)会产生剂量依赖性有害影响,应努力减少患者对电离辐射的暴露。胆总管结石患者通常会暴露于电离辐射,因为包括微创胆总管探查术(MICBDE)和内镜逆行胰胆管造影术(ERCP)在内的透视引导下干预措施是清除胆总管结石的首选治疗方式。然而,这两种治疗方式之间的辐射暴露和透视时间(FTs)尚未进行比较。因此,本研究旨在比较胆总管结石患者接受MICBDE和ERCP时的透视时间和辐射暴露。
这是一项回顾性分析,对2021年5月至2023年6月在学术转诊中心由一名外科医生进行的MICBDE前瞻性维护数据库进行分析,并与2020年1月至2021年2月期间进行的所有ERCP的回顾性分析进行比较。比较了MICBDE和ERCP之间的患者人口统计学、手术细节、透视细节和术后结果。该研究在位于美国西南部的单一机构学术转诊中心进行。总共109例胆总管结石患者被分为两组。共有53例(48.62%)患者接受了ERCP,56例(51.38%)患者接受了MICBDE。纳入标准是所有出现胆总管结石并随后接受ERCP或MICBDE的患者。因非胆总管结石相关原因接受ERCP的患者被排除。主要结局包括以分钟为单位测量的透视时间和以毫戈瑞(mGy)为单位测量的辐射暴露。次要结局是胆总管的成功清除、并发症、手术时间和再次干预。
ERCP(3.1分钟)和MICBDE(1.54分钟)之间的透视时间存在显著差异(P <.001)。ERCP组(38 mGy)和MICBDE组(38.41 mGy)之间的辐射暴露中位数无统计学差异(P =.88)。两组胆总管清除的技术成功率相似(MICBDE组为91%,ERCP组为93%;P =.711)。
MICBDE相对于ERCP的优势包括在胆囊切除术时治疗胆总管结石,这降低了额外麻醉发作的风险,并有可能缩短住院时间。本研究表明,MICDBE的透视时间比ERCP短,且辐射暴露相当。鉴于MICBDE的优势,在进行腹腔镜胆囊切除术时应强烈考虑采用。