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攻克胆总管:微创经胆囊管胆总管探查术与内镜逆行胰胆管造影术的疗效比较

Conquering the common bile duct: outcomes in minimally invasive transcystic common bile duct exploration versus ERCP.

作者信息

DeJesus Jana, Horani Keenan, Brahmbhatt Kush, Mesa Camila Franco, Samreen Sarah, Moffett Jennifer M

机构信息

Department of Surgery, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-1172, USA.

School of Medicine, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-1172, USA.

出版信息

Surg Endosc. 2024 Dec;38(12):7552-7562. doi: 10.1007/s00464-024-11228-5. Epub 2024 Sep 17.

Abstract

INTRODUCTION

Given the increasing interest for surgeons to reclaim the common bile duct in managing choledocholithiasis, there is a growing movement to perform common bile duct exploration (CBDE). Advantages of concomitant CBDE with cholecystectomy include fewer anesthetic events and decreased length of stay. As there is a paucity of literature evaluating the use of the robotic platform for CBDE, our study aims to compare intraoperative and post-operative outcomes between robotic-assisted one-stage and two-stage management of choledocholithiasis.

METHODS

A retrospective chart review was performed from May 1, 2022 to December 31, 2023, identifying patients with choledocholithiasis who underwent robot-assisted laparoscopic cholecystectomy and transcystic CBDE with choledochoscopy (one-stage management). Preoperative, intraoperative, and post-operative variables were compared to a control group of subjects with choledocholithiasis who underwent laparoscopic cholecystectomy with pre- or post-operative ERCP (two-stage management). Statistical analysis was performed using Chi-squared, Fisher's exact, Student's T, or Mann-Whitney test.

RESULTS

Fifty-three subjects who underwent one-stage management and 101 subjects who underwent two-stage management met inclusion criteria. Groups had similar demographics and medical history. Time to CBD clearance (45.2 h vs 47.0 h, p = .036), total length of stay (3.9 days vs 5.1 days, p = .007), fluoroscopy time (70.3 s vs 151.4 s, p < .001), and estimated radiation dose (23.0 mSv vs 40.3 mSv, p = .002) were significantly lower in the one-stage group compared to two-stage. Clearance rates, complication rates, and 30-day readmission rates were similar for both groups. Total length of stay and radiation exposure remained significantly lower on subanalysis comparing one-stage management to two-stage management with ERCP either before or after cholecystectomy.

CONCLUSION

Robotic-assisted laparoscopic cholecystectomy with transcystic common bile duct exploration via choledochoscopy is a safe and feasible option in the management of choledocholithiasis. It offers a shorter time to duct clearance, shorter length of stay, and less radiation exposure when compared to two-stage management.

摘要

引言

鉴于外科医生在处理胆总管结石时对重新利用胆总管的兴趣日益增加,进行胆总管探查(CBDE)的趋势也在不断增长。胆总管探查与胆囊切除术同时进行的优点包括减少麻醉相关事件和缩短住院时间。由于评估机器人平台用于胆总管探查的文献较少,我们的研究旨在比较机器人辅助一期和二期治疗胆总管结石的术中及术后结果。

方法

对2022年5月1日至2023年12月31日期间进行回顾性病历审查,确定接受机器人辅助腹腔镜胆囊切除术和经胆囊镜胆总管探查术(一期治疗)的胆总管结石患者。将术前、术中和术后变量与接受腹腔镜胆囊切除术并在术前或术后进行内镜逆行胰胆管造影(ERCP)(二期治疗)的胆总管结石对照组进行比较。使用卡方检验、Fisher精确检验、学生t检验或Mann-Whitney检验进行统计分析。

结果

53例行一期治疗的患者和101例行二期治疗的患者符合纳入标准。两组的人口统计学和病史相似。一期治疗组的胆总管清除时间(45.2小时对47.0小时,p = 0.036)、总住院时间(3.9天对5.1天,p = 0.007)、透视时间(70.3秒对151.4秒,p < 0.001)和估计辐射剂量(23.0毫西弗对40.3毫西弗,p = 0.002)均显著低于二期治疗组。两组的清除率、并发症发生率和30天再入院率相似。在将一期治疗与胆囊切除术前后进行ERCP的二期治疗进行亚组分析时,总住院时间和辐射暴露仍显著较低。

结论

机器人辅助腹腔镜胆囊切除术联合经胆囊镜胆总管探查术是治疗胆总管结石的一种安全可行的选择。与二期治疗相比,它能缩短胆管清除时间、缩短住院时间并减少辐射暴露。

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