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在一家三级医院的非传染性疾病患者中药物依从性的描述性横断面研究。

Medication Adherence among Patients with Non-Communicable Diseases in a Tertiary Hospital: A Descriptive Cross-sectional Study.

机构信息

National Academy of Medical Sciences, Bir Hospital Nursing Campus, Mahankal, Kathmandu, Nepal.

National Academy of Medical Sciences, Bir Hospital, Mahankal, Kathmandu, Nepal .

出版信息

JNMA J Nepal Med Assoc. 2024 Jun 30;62(275):433-438. doi: 10.31729/jnma.8650.

DOI:10.31729/jnma.8650
PMID:39369417
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11455636/
Abstract

INTRODUCTION

Non-communicable diseases (NCDs) are a leading cause of mortality, with a projected rise from 38 million in 2012 to 52 million by 2030. Among NCDs, hypertension, diabetes and Chronic Obstructive Pulmonary Disease are the major burdens in healthcare today, requiring long-term therapies and a significant effort in maintaining treatment adherence.

METHODS

A descriptive cross-sectional study design was adopted to determine medication adherence among patients with non-communicable diseases using non-probability, consecutive sampling techniques after ethical approval from same institute (Reference number: 524). Medication adherence was assessed on 322 patients attending the outpatient department, using a structured interview schedule, after getting Ethical approval from the Institution Review Committee. Morisky medication adherence scale (MMAS-4), Culig adherence Scale, and Beliefs about Medications (BMQ) tool were used to determine the adherence level, causes of non-adherence and belief in medication respectively. Data was coded and analysed using SPSS version 16. Descriptive statistics were used to summarise the data.

RESULTS

The study population exhibited a mean age of 58 ± 12.80 years, with male participants 190 (59.01%). The present study revealed that 148 (45.96%) of the participants have a high adherence level to prescribed medication, and 246 (76.40%) strongly believed that without medication they would be very sick and life would be impossible.

CONCLUSIONS

The study found that less than half of participants fully adhered to prescribed medicine, with forgetfulness identified as a primary cause of non-compliance.

摘要

简介

非传染性疾病(NCDs)是导致死亡的主要原因之一,预计到 2030 年,这一数字将从 2012 年的 3800 万增加到 5200 万。在 NCDs 中,高血压、糖尿病和慢性阻塞性肺疾病是当今医疗保健的主要负担,需要长期治疗,并需要付出很大努力来维持治疗的依从性。

方法

本研究采用描述性横断面研究设计,在获得同机构伦理批准(参考编号:524)后,采用非概率、连续抽样技术,确定非传染性疾病患者的药物依从性。在获得机构审查委员会的伦理批准后,使用结构化访谈表评估了 322 名在门诊就诊的患者的药物依从性。使用 Morisky 药物依从性量表(MMAS-4)、Culig 依从性量表和药物信念(BMQ)工具分别确定依从水平、不依从的原因和对药物的信念。使用 SPSS 版本 16 对数据进行编码和分析。使用描述性统计数据总结数据。

结果

研究人群的平均年龄为 58 ± 12.80 岁,男性参与者 190 人(59.01%)。本研究表明,148 名(45.96%)参与者对规定药物的依从性很高,246 名(76.40%)强烈认为没有药物他们会病得很重,生活将无法继续。

结论

研究发现,不到一半的参与者完全遵守规定的药物治疗,忘记是不遵守的主要原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/11455636/caa761571ed9/JNMA-62-275-433-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/11455636/caa761571ed9/JNMA-62-275-433-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2b9/11455636/caa761571ed9/JNMA-62-275-433-g1.jpg

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Non-adherence to anti-hypertensive medications in a low-resource country Nepal: a systematic review and meta-analysis.资源匮乏国家尼泊尔患者对抗高血压药物的不依从性:一项系统评价与荟萃分析
Ann Med Surg (Lond). 2023 Jul 19;85(9):4520-4530. doi: 10.1097/MS9.0000000000001088. eCollection 2023 Sep.
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Interventions to promote medication adherence for chronic diseases in India: a systematic review.促进印度慢性病药物依从性的干预措施:系统评价。
Front Public Health. 2023 Jun 16;11:1194919. doi: 10.3389/fpubh.2023.1194919. eCollection 2023.
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Factors Associated with Medication Adherence among Patients with Type 2 Diabetes Mellitus: A Hospital-Based Cross-Sectional Study in Nepal.
与尼泊尔基于医院的 2 型糖尿病患者药物治疗依从性相关的因素:一项横断面研究。
Int J Environ Res Public Health. 2023 Jan 14;20(2):1537. doi: 10.3390/ijerph20021537.
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Prevalence of medication adherence and its associated factors among patients with noncommunicable disease in rural Puducherry, South India - A facility-based cross-sectional study.印度南部本地治里农村地区非传染性疾病患者的药物依从性患病率及其相关因素——一项基于机构的横断面研究。
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