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本文引用的文献

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Longitudinal effects of medication nonadherence on glycemic control.药物治疗不依从对血糖控制的纵向影响。
Ann Pharmacother. 2014 May;48(5):562-70. doi: 10.1177/1060028014526362. Epub 2014 Feb 28.
2
The adherence to medications in diabetic patients in rural Kerala, India.印度喀拉拉邦农村地区糖尿病患者的药物依从性。
Asia Pac J Public Health. 2015 Mar;27(2):NP513-23. doi: 10.1177/1010539513475651. Epub 2013 Feb 14.
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The impact of treatment noncompliance on mortality in people with type 2 diabetes.治疗不依从对 2 型糖尿病患者死亡率的影响。
Diabetes Care. 2012 Jun;35(6):1279-84. doi: 10.2337/dc11-1277. Epub 2012 Apr 17.
4
Adherence to anti-diabetic drug therapy and self management practices among type-2 diabetics in Nigeria.尼日利亚2型糖尿病患者的抗糖尿病药物治疗依从性及自我管理实践
Pharm World Sci. 2008 Dec;30(6):876-83. doi: 10.1007/s11096-008-9243-2. Epub 2008 Sep 11.
5
Predictive validity of a medication adherence measure in an outpatient setting.门诊环境中药物依从性测量的预测效度。
J Clin Hypertens (Greenwich). 2008 May;10(5):348-54. doi: 10.1111/j.1751-7176.2008.07572.x.
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Medication compliance and persistence: terminology and definitions.药物依从性和持续性:术语与定义。
Value Health. 2008 Jan-Feb;11(1):44-7. doi: 10.1111/j.1524-4733.2007.00213.x.
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A systematic review of adherence with medications for diabetes.一项关于糖尿病药物治疗依从性的系统评价。
Diabetes Care. 2004 May;27(5):1218-24. doi: 10.2337/diacare.27.5.1218.
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Burden of non-communicable diseases in South Asia.南亚非传染性疾病的负担
BMJ. 2004 Apr 3;328(7443):807-10. doi: 10.1136/bmj.328.7443.807.

印度南部本地治里农村地区非传染性疾病患者的药物依从性患病率及其相关因素——一项基于机构的横断面研究。

Prevalence of medication adherence and its associated factors among patients with noncommunicable disease in rural Puducherry, South India - A facility-based cross-sectional study.

作者信息

Yuvaraj K, Gokul S, Sivaranjini K, Manikandanesan S, Murali Sharan, Surendran Gayathri, Majella Marie Gilbert, Kumar S Ganesh

机构信息

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

出版信息

J Family Med Prim Care. 2019 Feb;8(2):701-705. doi: 10.4103/jfmpc.jfmpc_350_18.

DOI:10.4103/jfmpc.jfmpc_350_18
PMID:30984698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6436260/
Abstract

BACKGROUND

Trends in morbidity and mortality due to noncommunicable diseases (NCDs) are rising because of poor control status. Medication nonadherence is one of the most common and modifiable causes of inadequate control status.

OBJECTIVES

To determine the prevalence of drug adherence among patients with NCD in rural Puducherry.

METHODS

A facility-based cross-sectional study was done among 260 patients with NCD receiving treatment from rural primary health center in Puducherry during February and March 2018. Information regarding sociodemographic profile and household was collected using pretested semi-structured questionnaire. Morisky Medication Adherence Scale was done to assess the adherence. We calculated adjusted prevalence ratios (aPRs) to identify the factors associated with medication adherence.

RESULTS

Among the 260 participants, 42.7% belonged to elderly age group; 66.2% were females; 44% did not have any formal education; 70% were unemployed. The majority were suffering from hypertension (71.2%) followed by diabetes (56.2%). This study found that almost one-third (32.7%) of the study participants were not properly adherent to medications. Elderly [aPR 2.51 95% confidence interval (CI): 1.70-3.70] and female participants (aPR 1.64 95% CI: 1.04-2.58) were found to have more chance being nonadherent to medications after adjusting for possible confounding variables.

CONCLUSION

This study reported that almost one-third of the study participants were nonadherent to medications. Elderly age group and female gender were found to be the determinants of nonadherence. Corrective measures need to be started at patient level first by motivating and educating them regarding the importance of drug intake.

摘要

背景

由于控制状况不佳,非传染性疾病(NCDs)的发病率和死亡率呈上升趋势。药物治疗不依从是控制状况不佳最常见且可改变的原因之一。

目的

确定在本地治里农村地区非传染性疾病患者中药物依从性的患病率。

方法

2018年2月至3月期间,在本地治里农村初级卫生中心接受治疗的260名非传染性疾病患者中进行了一项基于机构的横断面研究。使用预先测试的半结构化问卷收集有关社会人口学特征和家庭的信息。采用莫里isky药物依从性量表来评估依从性。我们计算了调整后的患病率比(aPRs)以确定与药物依从性相关的因素。

结果

在260名参与者中,42.7%属于老年年龄组;66.2%为女性;44%没有接受过任何正规教育;70%失业。大多数人患有高血压(71.2%),其次是糖尿病(56.2%)。本研究发现,近三分之一(32.7%)的研究参与者未正确坚持服药。在调整可能的混杂变量后,发现老年参与者(aPR 2.51,95%置信区间(CI):1.70 - 3.70)和女性参与者(aPR 1.64,95%CI:1.04 - 2.58)不坚持服药的可能性更大。

结论

本研究报告称,近三分之一的研究参与者未坚持服药。发现老年年龄组和女性是不依从的决定因素。首先需要在患者层面采取纠正措施,通过激励和教育他们认识到服药的重要性。