Griffith David C, Fall Amary, Carter Mihaela, Traut Caroline C, Sop Joel, Hansoti Bhakti, Gebo Kelly A, Mostafa Heba H, Blankson Joel N
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Open Forum Infect Dis. 2024 Sep 23;11(10):ofae549. doi: 10.1093/ofid/ofae549. eCollection 2024 Oct.
We present a case of mpox recurrence in a transgender woman with AIDS. Her recurrent lesions required several courses of antiviral therapy over a 5-month period and her monkeypox viral genome was subsequently noted to have tecovirimat resistance mutations. Interestingly, she developed a robust orthopoxvirus-specific T-cell response.
我们报告了一例患有艾滋病的跨性别女性猴痘复发的病例。她的复发性皮损在5个月内需要接受多个疗程的抗病毒治疗，随后发现她的猴痘病毒基因组存在对特考韦瑞有抗性的突变。有趣的是，她产生了强烈的正痘病毒特异性T细胞反应。
