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(1,2,4a,6,8,8a)-1-(3-羟基丙酰基)-1,3,6,8-四甲基-1,2,4a,5,6,7,8,8a-八氢萘-2-羧酸

(1,2,4a,6,8,8a)-1-(3-Hy-droxy-propano-yl)-1,3,6,8-tetra-methyl-1,2,4a,5,6,7,8,8a-octa-hydronaphthalene-2-carb-oxy-lic acid.

作者信息

Botha Christo J, Fouche Gerda, Malan Frederick P

机构信息

Department of Paraclinical Sciences, Faculty of Veterinary Science, Onderstepoort, University of Pretoria, Pretoria, South Africa.

Department of Chemistry, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa.

出版信息

IUCrdata. 2024 Sep 17;9(Pt 9):x240885. doi: 10.1107/S241431462400885X. eCollection 2024 Sep.

DOI:10.1107/S241431462400885X
PMID:39371674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11451037/
Abstract

The mol-ecular structure of CHO, (+)-diplodiatoxin, is described, whereby the absolute configuration of the structure of diplodiatoxin has been confirmed by single-crystal X-ray diffraction. Diplodiatoxin crystallizes in the chiral 422 space group with one mol-ecule in the asymmetric unit.

摘要

描述了CHO,(+)-双盘梭孢菌素的分子结构,双盘梭孢菌素结构的绝对构型已通过单晶X射线衍射得到确认。双盘梭孢菌素在手性422空间群中结晶,不对称单元中有一个分子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/60d58877a626/x-09-x240885-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/ba8c4ac8496c/x-09-x240885-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/0895b2cad4b6/x-09-x240885-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/60d58877a626/x-09-x240885-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/ba8c4ac8496c/x-09-x240885-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/0895b2cad4b6/x-09-x240885-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc86/11451037/60d58877a626/x-09-x240885-fig3.jpg

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本文引用的文献

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Failure of diplodiatoxin to induce diplodiosis in juvenile goats.双盘孢毒素未能在幼年山羊中诱发双盘孢霉病。
Onderstepoort J Vet Res. 2020 Mar 5;87(1):e1-e4. doi: 10.4102/ojvr.v87i1.1712.
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Use of intensity quotients and differences in absolute structure refinement.强度商数的使用及绝对结构精修中的差异
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Ecotoxicol Environ Saf. 2002 Jul;52(3):267-72. doi: 10.1006/eesa.2002.2200.
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Toxicity of Diplodia maydis in farm and laboratory animals.玉米赤霉在农场动物和实验动物中的毒性。
Food Chem Toxicol. 1985 Mar;23(3):349-53. doi: 10.1016/0278-6915(85)90070-5.