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足月分娩新生儿中早期与延迟脐带结扎对血红蛋白水平影响的比较

Comparison of the Effects of Early Versus Delayed Cord Clamping on Haemoglobin Levels in Neonates Delivered at Term.

作者信息

Saghir Fouzia, Nazeef Sana, Khalid Marina, Iqbal Aisha

机构信息

Obstetrics and Gynaecology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, PAK.

Obstetrics and Gynaecology, Services Institute of Medical Sciences, Lahore, PAK.

出版信息

Cureus. 2024 Sep 5;16(9):e68714. doi: 10.7759/cureus.68714. eCollection 2024 Sep.

DOI:10.7759/cureus.68714
PMID:39371720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11453146/
Abstract

BACKGROUND

The foetus is connected to the placenta via the umbilical cord, which enters through the abdomen at the umbilicus. A venous catheter for infusion and medication may be inserted via the umbilical vein, as it is directly related to the central circulation. Since delayed cord clamping increases iron storage after birth, it may help prevent anaemia in later infancy.

METHODS

This randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology at Aziz Bhatti Shaheed Teaching Hospital, Pakistan, over a period of six months, from August 2021 to January 2022. A total of 70 females were enrolled. The neonates were randomly divided into two groups using the lottery method. In group 1, neonates underwent early cord clamping, while in group 2, neonates underwent delayed cord clamping after delivery. Haemoglobin levels were noted and analysed using IBM SPSS Statistics for Windows, Version 20 (Released 2011; IBM Corp., Armonk, New York).

RESULTS

The mean age of patients in the early cord clamping group was 26.80±7.59 years, and in the delayed cord clamping group, it was 28.14±6.12 years. The mean haemoglobin level in the early cord clamping group was 13.84±1.74, while in the delayed cord clamping group, it was 16.34±1.90 (p-value=0.001).

CONCLUSION

In neonates born at term, the mean haemoglobin level in the delayed cord clamping group was significantly higher than that in the early cord clamping group.

摘要

背景

胎儿通过脐带与胎盘相连,脐带经脐部进入腹部。由于脐静脉与中心循环直接相关,可经脐静脉插入用于输液和给药的静脉导管。由于延迟脐带结扎可增加出生后的铁储存,可能有助于预防婴儿后期贫血。

方法

本随机对照试验于2021年8月至2022年1月在巴基斯坦阿齐兹·巴蒂·沙希德教学医院妇产科进行,为期6个月。共纳入70名女性。采用抽签法将新生儿随机分为两组。第1组新生儿进行早期脐带结扎,第2组新生儿在分娩后进行延迟脐带结扎。记录血红蛋白水平,并使用IBM SPSS Statistics for Windows 20版(2011年发布;IBM公司,纽约州阿蒙克)进行分析。

结果

早期脐带结扎组患者的平均年龄为26.80±7.59岁,延迟脐带结扎组为28.14±6.12岁。早期脐带结扎组的平均血红蛋白水平为13.84±1.74,而延迟脐带结扎组为16.34±1.90(p值=0.001)。

结论

足月出生的新生儿中,延迟脐带结扎组的平均血红蛋白水平显著高于早期脐带结扎组。

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Delayed umbilical cord clamping in elective and nonelective term Cesarean delivery.择期及非择期足月剖宫产术中延迟脐带结扎
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